DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment CG8878 and ttbk2

DIOPT Version :9

Sequence 1:	NP_001260913.1	Gene:	CG8878 / 36302	FlyBaseID:	FBgn0027504	Length:	1004	Species:	Drosophila melanogaster
Sequence 2:	XP_012824152.2	Gene:	ttbk2 / 780299	XenbaseID:	XB-GENE-493335	Length:	1298	Species:	Xenopus tropicalis

Alignment Length:	569	Identity:	123/569 - (21%)
Similarity:	201/569 - (35%)	Gaps:	158/569 - (27%)

- Green bases have known domain annotations that are detailed below.

  Fly   494 QKLRSRGSKHLDNNPTEYKF--LPTEEEHVFLIDFGLASKFQDR-GVHRPFIMDQRRA---HDGT 552
            :.:.|.|..|.|..|:.:..  .|:.....:::|||||.:|.:. |..||     .||   ..||
Frog   130 ESIHSVGFLHRDIKPSNFAMGRFPSTCRKCYMLDFGLARQFTNSCGDVRP-----PRAVAGFRGT 189

  Fly   553 LEFTSRDAH----LGAHSRRSDLECLGYNLLYWSEGYLPWKDVAQQQQQEKVHRAKELFMTDVPE 613
            :.:.|.:||    :|.|   .||..|.|.|:.:..|.|||:.:   :.:|:|...||.:...:
Frog   190 VRYASVNAHRNREMGRH---DDLWSLFYMLVEFVVGQLPWRKI---KDKEQVGSIKERYEHRL-- 246

  Fly   614 MLRQFYGKQVPKYLGEFLLQIGQLAYQERPNYERYRKIFKREYQRLGY---DPCQMRLSSEEILR 675
            ||     |.:|.....||..|..|.|..:|:|:....:|....:..|.   ||.....|..
Frog   247 ML-----KHLPPEFSVFLEHIIGLDYFTKPDYQLLVSVFDNSMKTFGVLESDPFDWEKSGS---- 302

  Fly   676 TCVSTKDVVDGSKCDIFELNNKAAVNVMRNSTLSTPFQEHSLTNRVSPKNLRSKSNKKTTKKKFS 740
                     |||              ::..:|.:||    .|..|::|..:...:.....
Frog   303 ---------DGS--------------LITTTTSTTP----QLHTRLTPAAIGIANATPIP----- 335

  Fly   741 WAEVLSQDPDQIARERAVKEFEREETICPLESRLPRRYEGKPTYAILDMEQRRREKGLVVQEHIE 805
             .::|.::.|::..:....:.|....:.....:||    |.|.:      ||.:||.:
Frog   336 -GDLLRENTDEVFPDEQFSDGENGIPVIVSPEKLP----GSPNH------QRLQEKDV------- 382

  Fly   806 EEEEDADE------------DDEEEN------------------QEAMDID----------QEED 830
            .||.||:.            :||..|                  :.|.|.|          ...:
Frog   383 WEEMDANRNKIKMGICKAATEDENSNGQGNGHAPSLGSPIRVRSETAQDRDVPLLRKLRTIHSFE 447

  Fly   831 GEAADSAEGEDESDRSMEGSDCSDHSQKRAR-GRP--KGTSRKQTTSRQAQPHQNQPPVKVH--- 889
            .|...:.|.:.::|:.::  :|.:..|:... |.|  :|:......|::..|...|.....|
Frog   448 LERRMTLESKPDADKFLD--NCPEKPQRETNTGGPLAEGSCASPRQSKKTVPPTAQADHAWHYDD 510

  Fly   890 ----RGVGRPGKNSGVVKLAAGAVSKNRTTPLSAVASNKRGCATRKENSTLASATGEGERKLKSG 950
                .| .:||..|....| .||.|.      ..||.|...|  |:|..:......:.:|.||..
Frog   511 EYIPEG-SKPGSASSPEHL-DGAGSN------GFVAVNLSSC--RQEVDSKEWVIVDKDRDLKDF 565

  Fly   951 RTRRALYKTEPKHGEHDAENNSSLLVVQNLYGEYD-------DENNYGK 992
            .|.:....|    |....|....|.|:.:...||:       |.|.:.|
Frog   566 GTNQGQKLT----GSPSEEEPEVLQVLDDSPQEYNAKLSPWTDNNTHNK 610

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG8878	NP_001260913.1	PKc_like	112..>286	CDD:304357
		SPS1	123..>284	CDD:223589
		SPS1	<491..756	CDD:223589	64/274 (23%)
		PKc_like	<517..652	CDD:304357	42/142 (30%)
ttbk2	XP_012824152.2	PKc_like	20..281	CDD:419665	48/168 (29%)
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	0	0.000	Not matched by this tool.
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	0	0.000