Protein Alignment bsd and Vrk3

DIOPT Version :10

• Sequence 1: NP_610733.1
• Gene: bsd / 36302
• FlyBaseID: FBgn0027504
• Length: 1004
• Species: Drosophila melanogaster
• Sequence 2: NP_001005561.2
• Gene: Vrk3 / 361565
• RGDID: 1549692
• Length: 462
• Species: Rattus norvegicus
• Alignment Length: 677
• Identity: 122/677 - (18%)
• Similarity: 196/677 - (28%)
• Gaps: 293/677 - (43%)

  Fly    14 RSARKRKRSAVKAAEKRQRLSGGSSSANGFEFHENDD----EESCSSAGSAAGTEADPPTLLHTP 74
            |.:::...|:.:.:.|:.:.|...:|. ....|.:.|    :::.||...|.||.:...|...:|
  Rat    55 RGSKRDLNSSSETSPKKVKWSRTVTSL-PLSLHSDYDSSGSDDTLSSPDRATGTRSRSQTPKGSP 118

  Fly    75 QARSLLLTGASIASDHNNSSVMESPRPVYTLRPSVV--------NGTILRDVLSKAWRLGRPIGK 131
            .|..|                  |||   ||:.|.|        .||.|.|...|.|.||....:
  Rat   119 LANRL------------------SPR---TLKRSRVTTSLQALPTGTELTDQNGKHWTLGTLQTR 162

  Fly   132 GNFGEIFLASDDTVCPASSETAKYVVKIEPHS-NGPLFVEIHCLINTSRNNDLSDAAEDAASLPA 195
            .:.|.::.|...:...:.|.|.|:...::..| :|.||.|         .|....||:   .|..
  Rat   163 DDQGILYAAEPTSAISSESRTQKWRFSLKLDSKDGRLFNE---------QNFFQRAAK---PLQV 215

  Fly   196 PQTHVLSRGPPSGIPSFIASGTHYFGDVRYRFLVLPRFDRDLHSLIKNSR---VQQKSLLVLAVH 257
            .:.......|...||:.|..|.|   ..:|||||.|...|.|.|.:.::.   |.::.:|.:|..
  Rat   216 NKWKKRCLTPLLAIPTCIGFGVH---QDKYRFLVFPSLGRSLQSALDDNPKHVVSERCMLQVACR 277

  Fly   258 IINVLENLHDKGYCHNDIKAQNLMVSKCKYLRRQVVPKGNGYEDHYEEKQQTTDSGNSSEQETND 322
            :::.||.||:..|.|.::..:|:.|:
  Rat   278 LLDALEYLHEHEYVHGNLTTENVFVN--------------------------------------- 303

  Fly   323 DDYFLKSEKFALKKIVDIKQDEDEDDEDFDDGATSNSNNSNSLDVFHTPVNKKRSARNAIQFSGS 387
                                                                             
  Rat   304 ----------------------------------------------------------------- 303

  Fly   388 NPVRACRREKRNSMYEEMVKSHYLRPTKRISYREEFNEDGYPKETAENSDESPESSDNESDEFIP 452
                                                                             
  Rat   304 ----------------------------------------------------------------- 303

  Fly   453 PSSRRSVIKRGRSAQIATPKKTPVSTRASRQEKVKKEPNGDQKLRSRGSKHLDNNPTEYKFLPTE 517
                                                                          |.:
  Rat   304 --------------------------------------------------------------PED 306

  Fly   518 EEHVFLIDFGLASKFQDRGVHRPFIMDQRRAHDGTLEFTSRDAHLG-AHSRRSDLECLGYNLLYW 581
            ...|.|:.:|...::...|.|..:....|..|||.|||.|.|.|.| ..||||||:.|||.:|.|
  Rat   307 LSQVTLVGYGFTYRYCPGGKHVAYKEGSRSLHDGDLEFISMDVHKGCGPSRRSDLQTLGYCMLKW 371

  Fly   582 SEGYLPWKDVAQQQQQEKVHRAKELFMTDVPEMLRQFYGK--QVPKYLGEFLLQIGQLAYQERPN 644
            ..|.|||.:..  ...|::.:.|:.:. |.||.|....|:  :..:.|.|:|..:..|.|:|:|.
  Rat   372 LYGSLPWTNCL--PNTEEITKQKQKYQ-DNPEPLVGLCGRWNKTSETLREYLKVVMALDYEEKPP 433

  Fly   645 YERYR---KIFKREYQRLGYDPCQMRL 668
            |...|   ::..:..:...|||..:::
  Rat   434 YATLRNNLEVLLQNMRVSPYDPLDLQM 460

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
bsd	NP_610733.1	Protein Kinases, catalytic domain	112..>286	CDD:473864	48/177 (27%)
		Protein Kinases, catalytic domain	<517..652	CDD:473864	47/140 (34%)
Vrk3	NP_001005561.2	zinc_ribbon_2	13..32	CDD:433054
		Protein Kinases, catalytic domain	143..445	CDD:473864	96/550 (17%)