Protein Alignment bsd and Vrk2

DIOPT Version :10

• Sequence 1: NP_610733.1
• Gene: bsd / 36302
• FlyBaseID: FBgn0027504
• Length: 1004
• Species: Drosophila melanogaster
• Sequence 2: NP_001388334.1
• Gene: Vrk2 / 360991
• RGDID: 1311585
• Length: 503
• Species: Rattus norvegicus
• Alignment Length: 730
• Identity: 156/730 - (21%)
• Similarity: 244/730 - (33%)
• Gaps: 286/730 - (39%)

  Fly   103 YTLRPSVVNGTILRDVLSKAWRLGRPIGKGNFGEIFLASDDTVCPAS--SETAKYVVKIEPHSNG 165
            |.|...:..|.||.|:....|.||:.||.|.||.|:||     .|.:  .:.|::|:|:|...||
  Rat     9 YKLPVPLPEGKILDDMEGNQWALGKMIGSGGFGLIYLA-----FPTNKPEKDARHVIKVEYQENG 68

  Fly   166 PLFVEIHCLINTSRNNDLSDAAEDAASLPAPQTHVLSRG-PPSGIPSFIASGTHYFGDVRYRFLV 229
            |||.|:...             :.||.....|..|..|. ...|:|.|...|...|....|||:|
  Rat    69 PLFSELKFY-------------QRAAKRECIQKWVKQRKLDYLGVPVFYGFGLTDFKGRSYRFMV 120

  Fly   230 LPRFDRDLHSLI-KNSRVQQKSLLVLAVHIINVLENLHDKGYCHNDIKAQNLMVSKCKYLRRQVV 293
            :.|...||..|: :|...::.::|.|.:.:::|||.:|:..|.|.||||.||::
  Rat   121 MERLGIDLQKLLNQNGAFKKLTVLQLGIRMLDVLEYIHENEYVHGDIKAANLLL----------- 174

  Fly   294 PKGNGYEDHYEEKQQTTDSGNSSEQETNDDDYFLKSEKFALKKIVDIKQDEDEDDEDFDDGATSN 358
                ||
  Rat   175 ----GY----------------------------------------------------------- 176

  Fly   359 SNNSNSLDVFHTPVNKKRSARNAIQFSGSNPVRACRREKRNSMYEEMVKSHYLRPTKRISYREEF 423
                                        :||
  Rat   177 ----------------------------ANP---------------------------------- 179

  Fly   424 NEDGYPKETAENSDESPESSDNESDEFIPPSSRRSVIKRGRSAQIATPKKTPVSTRASRQEKVKK 488
                                                                             
  Rat   180 ----------------------------------------------------------------- 179

  Fly   489 EPNGDQKLRSRGSKHLDNNPTEYKFLPTEEEHVFLIDFGLASKFQDRGVHRPFIMDQRRAHDGTL 553
                                          :.|:|.|:||:.::...|.|:.:..|.|:.|:|||
  Rat   180 ------------------------------DRVYLADYGLSYRYCPNGNHKQYHEDPRKGHNGTL 214

  Fly   554 EFTSRDAHLG-AHSRRSDLECLGYNLLYWSEGYLPWKDVAQQQQQEKVHRAKELFMTDVPE-MLR 616
            ||||.|||.| |.|||||:|.|||.:|.|..|.|||:  ...:....|..||...:.::|| :|:
  Rat   215 EFTSLDAHKGVAPSRRSDVEILGYCMLRWLCGKLPWE--TNLENPVAVQTAKTKLLDELPESVLK 277

  Fly   617 QFYGKQVPKYLGEFLLQIGQLAYQERPNYERYRKIFKREYQRLGYDPCQMRLSSEEI-LRTCVST 680
            ........:.|.||.:.:..|||..:|:|::.:||...:...||  |......::.: ::|.:..
  Rat   278 WTTSGSSCRELAEFFMYVHNLAYDAKPDYQKLKKILNPDGVPLG--PLDFSTKAQGVNMQTPIHR 340

  Fly   681 KDVVDGSKCDIFELNNKAAVNVMR---NSTLSTPFQEHS-------LTNRVSPKNLRSKSNKK-- 733
            |  ||..|. |.:..|:......|   ..|.:|..:|..       |::..:|:|.|::..::
  Rat   341 K--VDSPKA-IKKPANEFPTKYTRKVCGETRATWREEQEERRPAVLLSDLATPENSRTRKVREYS 402

  Fly   734 -TTKKKFSWAEVLSQDPDQIARERAVKEFEREETICPLESRLPR---RYEGKPT--YAILDMEQR 792
             |..:..|:.:..|....|.:..:...:..|.:.|     |.||   :|..|||  ..:.|:|..
  Rat   403 DTFSEMLSFRQTQSYPRFQGSHCKPYLDCTRRDPI-----RKPRPLPQYGSKPTGNLGVTDLESS 462

  Fly   793 RREKGLVVQEHIEEE 807
            .|....|:|..:.||
  Rat   463 PRFWPAVLQLTLSEE 477

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
bsd	NP_610733.1	Protein Kinases, catalytic domain	112..>286	CDD:473864	59/177 (33%)
		Protein Kinases, catalytic domain	<517..652	CDD:473864	52/136 (38%)
Vrk2	NP_001388334.1	Protein Kinases, catalytic domain	16..314	CDD:473864	116/548 (21%)