DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment CG8878 and CkIalpha

DIOPT Version :9

Sequence 1:	NP_001260913.1	Gene:	CG8878 / 36302	FlyBaseID:	FBgn0027504	Length:	1004	Species:	Drosophila melanogaster
Sequence 2:	NP_001162737.1	Gene:	CkIalpha / 32221	FlyBaseID:	FBgn0015024	Length:	337	Species:	Drosophila melanogaster

Alignment Length:	166	Identity:	55/166 - (33%)
Similarity:	84/166 - (50%)	Gaps:	12/166 - (7%)

- Green bases have known domain annotations that are detailed below.

  Fly   503 HLDNNPTEYKFLPTEEEH---VFLIDFGLASKFQDRGVHRPFIMDQRRAHDGTLEFTSRDAHLG- 563
            |.|..|.  .||.....|   :||||||||.||:|.......:..:.:...||..:.|.:||||
  Fly   137 HRDIKPD--NFLMGIGRHCNKLFLIDFGLAKKFRDPHTRHHIVYREDKNLTGTARYASINAHLGI 199

  Fly   564 AHSRRSDLECLGYNLLYWSEGYLPWKDVAQQQQQEKVHRAKELFMTDVPEMLRQFYGKQVPKYLG 628
            ..|||.|:|.|||.::|::.|.|||:.:....:|:|..:..|..|:...|:|    .|..|....
  Fly   200 EQSRRDDMESLGYVMMYFNRGVLPWQGMKANTKQQKYEKISEKKMSTPIEVL----CKGSPAEFS 260

  Fly   629 EFLLQIGQLAYQERPNYERYRKIFKREYQRLG--YD 662
            .:|.....|.::|:|:|...|::|:..::.|.  ||
  Fly   261 MYLNYCRSLRFEEQPDYMYLRQLFRILFRTLNHQYD 296

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG8878	NP_001260913.1	PKc_like	112..>286	CDD:304357
		SPS1	123..>284	CDD:223589
		SPS1	<491..756	CDD:223589	55/166 (33%)
		PKc_like	<517..652	CDD:304357	46/138 (33%)
CkIalpha	NP_001162737.1	PKc_like	19..284	CDD:304357	51/152 (34%)
CkIalpha	NP_001162737.1	Pkinase_Tyr	23..284	CDD:285015	51/152 (34%)
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_KOG1164
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	1	1.100	-	-	P	PTHR11909
Phylome	0	0.000	Not matched by this tool.
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
	2	2.000