DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment CG8878 and ZK507.1

DIOPT Version :9

Sequence 1:	NP_001260913.1	Gene:	CG8878 / 36302	FlyBaseID:	FBgn0027504	Length:	1004	Species:	Drosophila melanogaster
Sequence 2:	NP_499015.2	Gene:	ZK507.1 / 191336	WormBaseID:	WBGene00013978	Length:	331	Species:	Caenorhabditis elegans

Alignment Length:	248	Identity:	57/248 - (22%)
Similarity:	97/248 - (39%)	Gaps:	39/248 - (15%)

- Green bases have known domain annotations that are detailed below.

  Fly   500 GSKHLDNNPTEYKF-LPTEEEHVFLIDFGLASKFQ-DRGVHRPFIMDQRRAHDGTLEFTSRDAH- 561
            |..|.|..|..|.. ..::.|.::::|||||.|:: ..|..||  ...:....||..:.||.:|
Worm   111 GFLHRDIKPANYCIGYGSKSETIYVLDFGLARKYRLPNGQVRP--PRPKTKMIGTPRYCSRASHR 173

  Fly   562 ---LGAHSRRSDLECLGYNLLYWSEGYL-PWKDVAQQQQQEKVHRAKELFMTDVPEMLRQFYGKQ 622
               ||   ||.|.|...:..:...:..| .||.:.:.....|   .:|||     ..|:.:....
Worm   174 CEELG---RRDDYESWFFMFIDLVDTTLIDWKGLTRPDAYAK---KQELF-----TKLKTYEKHP 227

  Fly   623 VPKYLGEFLLQIGQLAYQERPNYERYRKIFKREYQRLGYDPCQMRLSSEEI---LRTCVSTKDVV 684
            :.|.:..:|   ..|.|.....:...|:.. .:|.|    .|::.|....:   ..||.| ....
Worm   228 MFKVISIYL---DNLVYDSEVKFGVLREAI-TDYAR----GCKLTLKEPLVWFNQSTCPS-PSTA 283

  Fly   685 DGSKCDIFELNNKAAVNVMRNSTLSTPFQEHSL-TNRVSPKNLRSKSNKKTTK 736
            .|:..      ::.|.|:...|..|...:|:|| .::....:..:..|||.::
Worm   284 PGTGA------SRMATNIDLKSIASDRNEENSLDRSKTGTLSFNNSKNKKPSR 330

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG8878	NP_001260913.1	PKc_like	112..>286	CDD:304357
		SPS1	123..>284	CDD:223589
		SPS1	<491..756	CDD:223589	57/248 (23%)
		PKc_like	<517..652	CDD:304357	34/140 (24%)
ZK507.1	NP_499015.2	SPS1	9..>168	CDD:223589	17/58 (29%)
ZK507.1	NP_499015.2	PKc_like	10..252	CDD:304357	38/156 (24%)
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_KOG1164
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	0	0.000	Not matched by this tool.
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	1	0.900