DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment CG8878 and F54H5.2

DIOPT Version :9

Sequence 1:	NP_001260913.1	Gene:	CG8878 / 36302	FlyBaseID:	FBgn0027504	Length:	1004	Species:	Drosophila melanogaster
Sequence 2:	NP_495347.1	Gene:	F54H5.2 / 186263	WormBaseID:	WBGene00018839	Length:	424	Species:	Caenorhabditis elegans

Alignment Length:	343	Identity:	75/343 - (21%)
Similarity:	126/343 - (36%)	Gaps:	86/343 - (25%)

- Green bases have known domain annotations that are detailed below.

  Fly   494 QKLRSRGSKHLDNNPTE----YKFLPTEEEHVFLIDFGLASKFQDRGVHRPFIMDQRRAHD---- 550
            :::...|..|.|..|..    ||....|.....::|||||.:|......:|..:..||..:
Worm   140 KQIHDIGFIHRDLKPANMALGYKTNNDECRFFHVLDFGLARQFVVSQSDQPSKLMMRRPRERSLF 204

  Fly   551 -GTLEFTSRDAHLGAHSRR-SDLECLGYNLLYWSEGYLPWKDVAQQQ---QQEKVHRAKELFMTD 610
             ||..:.|...|..|...| .||..:.| ||....|.|||.....::   :.:::|..:.:....
Worm   205 RGTTRYCSIRMHDRAEQGRVDDLWSILY-LLAELRGPLPWSSQNDKRVVGEMKRLHSDEVVLQNS 268

  Fly   611 VPEMLRQFYGKQVPKYLGEFLLQIGQLAYQERPNYERYRKIFKREYQRLGYDPCQMRLSSEEILR 675
            ..|.|      ::.|||       ..|.|..||:   |.|||                    :|.
Worm   269 PMEFL------EIAKYL-------RSLTYFHRPD---YHKIF--------------------MLL 297

  Fly   676 TCVSTKDVVDGSKCDIFELNNKAAVNVMRNSTLSTPFQEHSLTNRVSPKNLRSKSNKKTTKKKFS 740
            ..:.:|.....:  |.|:.          ...:||| ...|:|.  ||..|..::.||.:::|..
Worm   298 ISIMSKGKFSWN--DPFDW----------EMPISTP-PSKSITK--SPNQLSKETIKKASREKTL 347

  Fly   741 WAEVLSQDPDQIARERAVKEFEREETICPLESRLPRRYEGKPTYAILDMEQRRREKGLVVQEHIE 805
            ..|..|::..:.|::.::::..:|:                     |..|...:||..:..|.|.
Worm   348 SKEKTSKEDIKTAQKTSIEKDVKEK---------------------LSKEMASKEKISLSAEKIN 391

  Fly   806 EEEEDADEDDEEENQEAM 823
            ...|..:||:::|....|
Worm   392 MSAEKIEEDNKKEEYMRM 409

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG8878	NP_001260913.1	PKc_like	112..>286	CDD:304357
		SPS1	123..>284	CDD:223589
		SPS1	<491..756	CDD:223589	63/274 (23%)
		PKc_like	<517..652	CDD:304357	37/143 (26%)
F54H5.2	NP_495347.1	PKc_like	31..297	CDD:389743	45/193 (23%)
F54H5.2	NP_495347.1	rplD	317..>422	CDD:184900	26/117 (22%)
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_KOG1164
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	0	0.000	Not matched by this tool.
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	1	0.900