DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment CG8878 and F22H10.1

DIOPT Version :9

Sequence 1:	NP_001260913.1	Gene:	CG8878 / 36302	FlyBaseID:	FBgn0027504	Length:	1004	Species:	Drosophila melanogaster
Sequence 2:	NP_510698.2	Gene:	F22H10.1 / 184871	WormBaseID:	WBGene00017725	Length:	207	Species:	Caenorhabditis elegans

Alignment Length:	198	Identity:	38/198 - (19%)
Similarity:	75/198 - (37%)	Gaps:	62/198 - (31%)

- Green bases have known domain annotations that are detailed below.

  Fly   245 RVQQKSLLVLAVHIINVLENLHDKGYCHNDIKAQNLMVS--------------KCKYLRRQVVPK 295
            |:...:|:.:|..:.|.|..:||:|:.|.|:||.|::|:              |...::.|   .
Worm    18 RLSFNNLMRVAYTLGNTLCYIHDRGFIHRDLKADNVVVTFSNEVCTLKLIDFGKAIRIKDQ---N 79

  Fly   296 GNGYEDHYEEKQQTTDSGNSSEQETN---------DDDY------FLKSEKFA----LKKIVDIK 341
            ||....|    |...|....|:...|         :||:      .:|...|:    .::::|:|
Worm    80 GNQLPGH----QDGIDYSRCSQHSVNVILGIAPTQNDDWSSLVYLLMKMRGFSWGDTAEEMLDLK 140

  Fly   342 QDEDEDDEDFDDGATSNSNNSNSLDVFHTPVNKKRSARNAIQFSGSNPVRACRREKRNSMYEEMV 406
            ...:.|.:|.               :....:..::..|||:.       ....||....:.:::|
Worm   141 VQFENDPKDM---------------IAQDMMWMRQIYRNAVN-------EDMGRENNRGIVDKLV 183

  Fly   407 KSH 409
            ::|
Worm   184 QAH 186

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG8878	NP_001260913.1	PKc_like	112..>286	CDD:304357	15/54 (28%)
		SPS1	123..>284	CDD:223589	14/52 (27%)
		SPS1	<491..756	CDD:223589
		PKc_like	<517..652	CDD:304357
F22H10.1	NP_510698.2	PKc	<3..127	CDD:270622	26/115 (23%)
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_KOG1164
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	0	0.000	Not matched by this tool.
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	1	0.900