DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment CG8878 and E02H4.6

DIOPT Version :9

Sequence 1:	NP_001260913.1	Gene:	CG8878 / 36302	FlyBaseID:	FBgn0027504	Length:	1004	Species:	Drosophila melanogaster
Sequence 2:	NP_510377.1	Gene:	E02H4.6 / 183997	WormBaseID:	WBGene00008464	Length:	303	Species:	Caenorhabditis elegans

Alignment Length:	177	Identity:	45/177 - (25%)
Similarity:	72/177 - (40%)	Gaps:	45/177 - (25%)

- Green bases have known domain annotations that are detailed below.

  Fly   117 DVLSKAWRLGRPIGKGNFGEIFLASDDTVCPASSETAKYVVKIEPHSNGPLFVEIHCLINTSRNN 181
            |||...:::...||.|..|.||...|.   ...|.:...|:|:.|...|..|
Worm     6 DVLLGRYKIRFDIGPGRIGRIFAVLDQ---QDQSRSRVKVIKVLPMVAGEQF------------- 54

  Fly   182 DLSDAAEDAASLPAPQT--------HVLSRGPPSGIPSFIASGTHYFGDVRYRFLVLPRFDRDLH 238
                       |..|||        |:  || ..|:|:.|    .:|...|.|.:::.::...|.
Worm    55 -----------LDDPQTYNEFDFLNHL--RG-TIGVPNII----QHFQVGRERVMMMDKYLATLE 101

  Fly   239 SL---IKNSRVQQKSLLVLAVHIINVLENLHDKGYCHNDIKAQNLMV 282
            ..   ..:.|:...:::.:||.::||||.:|.||..|.|:|..|:|:
Worm   102 QFRTRCDDRRISDLNIIKIAVRLVNVLEAIHQKGVIHRDLKTTNVMI 148

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG8878	NP_001260913.1	PKc_like	112..>286	CDD:304357	45/177 (25%)
		SPS1	123..>284	CDD:223589	42/171 (25%)
		SPS1	<491..756	CDD:223589
		PKc_like	<517..652	CDD:304357
E02H4.6	NP_510377.1	PKc_like	<128..>259	CDD:389743	10/21 (48%)
E02H4.6	NP_510377.1	PKc_like	11..>168	CDD:389743	42/172 (24%)
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_KOG1164
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	0	0.000	Not matched by this tool.
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	1	0.900