DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment CG8878 and D2024.1

DIOPT Version :9

Sequence 1:	NP_001260913.1	Gene:	CG8878 / 36302	FlyBaseID:	FBgn0027504	Length:	1004	Species:	Drosophila melanogaster
Sequence 2:	NP_501151.1	Gene:	D2024.1 / 183947	WormBaseID:	WBGene00017050	Length:	359	Species:	Caenorhabditis elegans

Alignment Length:	253	Identity:	60/253 - (23%)
Similarity:	91/253 - (35%)	Gaps:	57/253 - (22%)

- Green bases have known domain annotations that are detailed below.

  Fly   494 QKLRSRGSKHLDNNPTEYKFLPTEE---EHVF-LIDFGLASKF----------QDRGVHRPFIMD 544
            :::...|..|.|..|..:.:..::|   ..|| |||||::|||          |..|..  |..:
Worm   137 KQMHDCGFLHHDLKPANFVWGQSDEVLTSRVFYLIDFGISSKFIRHIKGTPINQQNGFE--FRTE 199

  Fly   545 QRRAHD--GTLEFTSRDAHLGAHSRRSDLECLGYNLLYWSEGY--------LPWKDVAQQQQQEK 599
            .::.|.  ||.::||..||..|...|.|        .:||..|        |||          :
Worm   200 NKKVHSLVGTPKYTSPKAHAMADLGRGD--------DFWSLMYMIAELVKPLPW----------E 246

  Fly   600 VHRAKELFMTDVPEMLRQFYGKQVPKYLGEFLLQIGQLAYQERPNYERYRKIFKREYQRLGYDPC 664
            :..||.|..|.:...|:..||...   .|:....:....:...||||.....||..:.:.|....
Worm   247 ILEAKMLEKTKLKSKLKDLYGIDA---FGKIETMLQACTFHSFPNYEMIYHAFKDVFTKSGASWY 308

  Fly   665 QMRLSSEEILRTCVSTKDVVDGSKCDIFELNNKAAVNVMRNSTLSTPFQEHSLTNRVS 722
            ...:..|:|.|.      ..||.:..    .|....:|.:|.|....|:.......:|
Worm   309 DHSIGREKICRL------TNDGDRMP----RNHVDCSVGKNLTSDFIFERIHFNMHIS 356

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG8878	NP_001260913.1	PKc_like	112..>286	CDD:304357
		SPS1	123..>284	CDD:223589
		SPS1	<491..756	CDD:223589	60/253 (24%)
		PKc_like	<517..652	CDD:304357	42/158 (27%)
D2024.1	NP_501151.1	PKc_like	25..297	CDD:389743	46/182 (25%)
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_KOG1164
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	0	0.000	Not matched by this tool.
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	1	0.900