DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment CG8878 and C03C10.2

DIOPT Version :9

Sequence 1:	NP_001260913.1	Gene:	CG8878 / 36302	FlyBaseID:	FBgn0027504	Length:	1004	Species:	Drosophila melanogaster
Sequence 2:	NP_497820.2	Gene:	C03C10.2 / 182156	WormBaseID:	WBGene00007269	Length:	341	Species:	Caenorhabditis elegans

Alignment Length:	166	Identity:	39/166 - (23%)
Similarity:	73/166 - (43%)	Gaps:	34/166 - (20%)

- Green bases have known domain annotations that are detailed below.

  Fly   118 VLSKAWRLGRPIGKGNFGEIFLASDDTVCPASSETAKYVVKIEPHSNGPLFVEIHCLINTSRNND 182
            :....|.:...||.|.:|:||:..|   ...:.|.|   :||||        ::...:.|.|
Worm    45 IFMNRWSIEGVIGNGGYGQIFMVMD---VKKNDERA---MKIEP--------KLRAEVITKR--- 92

  Fly   183 LSDAAEDAASLPAPQTHVLSRGPPSGIPSFIASGTHYFGDVRYRFLVLPRFDRDLHSLIKNS--- 244
                      :...|..::.....:.||:..|||   |.| ::.|:::.....::....|.|
Worm    93 ----------MIMEQQVLMKMQGKTHIPTMYASG---FND-QFNFIIMQLLSMNVGDFRKRSPLG 143

  Fly   245 RVQQKSLLVLAVHIINVLENLHDKGYCHNDIKAQNL 280
            |:.::::..:|...:|.|:::||.||.|.|:|..|:
Worm   144 RLSKETVGRIAYQTLNALKDIHDMGYVHRDVKPANI 179

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG8878	NP_001260913.1	PKc_like	112..>286	CDD:304357	39/166 (23%)
		SPS1	123..>284	CDD:223589	39/161 (24%)
		SPS1	<491..756	CDD:223589
		PKc_like	<517..652	CDD:304357
C03C10.2	NP_497820.2	PKc_like	49..317	CDD:304357	39/162 (24%)
C03C10.2	NP_497820.2	Pkinase	50..303	CDD:278497	39/161 (24%)
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_KOG1164
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	0	0.000	Not matched by this tool.
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	1	0.900