DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment CG8878 and Y38H8A.3

DIOPT Version :9

Sequence 1:	NP_001260913.1	Gene:	CG8878 / 36302	FlyBaseID:	FBgn0027504	Length:	1004	Species:	Drosophila melanogaster
Sequence 2:	NP_502596.1	Gene:	Y38H8A.3 / 178315	WormBaseID:	WBGene00012637	Length:	308	Species:	Caenorhabditis elegans

Alignment Length:	181	Identity:	44/181 - (24%)
Similarity:	74/181 - (40%)	Gaps:	22/181 - (12%)

- Green bases have known domain annotations that are detailed below.

  Fly   494 QKLRSRGSKHLDNNPTEYKF-LP--TEEEHVFLIDFGLASKF--QDRGVHRPFIMDQRRAHDGTL 553
            :.|.:.|..|.|..|..|.. .|  .|...|:::|||:..||  .|..:.:|   .|.....||:
Worm   126 EDLHNIGYLHRDVKPGNYTIGRPELNEIRKVYILDFGMCRKFTGNDGTIRKP---RQAAGFRGTV 187

  Fly   554 EFTSRDAHLGAH-SRRSDLECLGYNLLYWSEGYLPWKDVAQQQQQEKVHRAKELFMTDVPEMLRQ 617
            ::.....||... .|:.|||...|..:..|.|.:||:.::...|   |.:||:....:    |..
Worm   188 KYAPISCHLQRELCRKDDLETWMYMQVELSHGTIPWQYISDMNQ---VGQAKQAIRNN----LGS 245

  Fly   618 FYGKQVPKYLGEFLLQIGQLAYQERPNYERYRKIFKREYQRLG------YD 662
            .:....|....:.:..:..:.|.:.|||:....:.::.|...|      ||
Worm   246 LFPPPCPHQFQDIMRMVDAMKYYDAPNYQAIYGMMRQAYGACGSNENAPYD 296

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG8878	NP_001260913.1	PKc_like	112..>286	CDD:304357
		SPS1	123..>284	CDD:223589
		SPS1	<491..756	CDD:223589	44/181 (24%)
		PKc_like	<517..652	CDD:304357	33/137 (24%)
Y38H8A.3	NP_502596.1	STKc_TTBK	16..281	CDD:270919	40/164 (24%)
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_KOG1164
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	0	0.000	Not matched by this tool.
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	1	0.900