DRSC - DRSC Integrative Ortholog Prediction Tool

back to: DIOPT - Ortholog Prediction Tool / DIOPT for Diseases and Traits

Protein Alignment CG8878 and C56C10.6

DIOPT Version :9

Sequence 1:	NP_001260913.1	Gene:	CG8878 / 36302	FlyBaseID:	FBgn0027504	Length:	1004	Species:	Drosophila melanogaster
Sequence 2:	NP_495333.1	Gene:	C56C10.6 / 174087	WormBaseID:	WBGene00016963	Length:	422	Species:	Caenorhabditis elegans

Alignment Length:	343	Identity:	77/343 - (22%)
Similarity:	128/343 - (37%)	Gaps:	81/343 - (23%)

- Green bases have known domain annotations that are detailed below.

  Fly   494 QKLRSRGSKHLDNNPTE----YKFLPTEEEHVFLIDFGLASKFQDRGVHRPFIMDQRRAHD---- 550
            :::...|..|.|..|..    ||....|.....::|||||.:|......:|..:..||..:
Worm   133 KQIHDIGFIHRDLKPANMALGYKTNNDECRFFHVLDFGLARQFVVSQSDQPSKLMMRRPRERSLF 197

  Fly   551 -GTLEFTSRDAHLGAHSRR-SDLECLGYNLLYWSEGYLPWKDVAQQQ---QQEKVHRAKELFMTD 610
             ||..:.|...|..|...| .||..:.| ||....|.|||...:.::   :.:::|..:.:....
Worm   198 RGTTRYCSIRMHDRAEQGRVDDLWSMVY-LLAELRGPLPWSSQSDKRVVGEMKRLHSDEVVLQNS 261

  Fly   611 VPEMLRQFYGKQVPKYLGEFLLQIGQLAYQERPNYERYRKIFKREYQRLGYDPCQMRLSSEEILR 675
            ..|.|      ::.|||       ..|.|..||:   |.|||             |.|.|
Worm   262 PMEFL------EIAKYL-------RSLTYFHRPD---YHKIF-------------MLLIS----- 292

  Fly   676 TCVSTKDVVDGSKCDIFELNNKAAVNVMRNSTLSTPFQEHSLTNRVSPKNLRSKSNKKTTKKKFS 740
                   |:...|   |..|:.....:..::|.|......|:|.  ||..|..::.||.:::|..
Worm   293 -------VMSKGK---FAWNDPFDWEMPISTTPSKSTPSKSVTK--SPAQLSKETVKKASREKTL 345

  Fly   741 WAEVLSQDPDQIARERAVKEFEREETICPLESRLPRRYEGKPTYAILDMEQRRREKGLVVQEHIE 805
            ..|..|::..:.||:.::::..:|:                     |..:...:||..:..|.|.
Worm   346 SKEKTSKEDIKTARKTSIEKDVKEK---------------------LSKDMASKEKISLSAEKIN 389

  Fly   806 EEEEDADEDDEEENQEAM 823
            ...|..:||:::|....|
Worm   390 MSAEKIEEDNKKEEYMRM 407

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG8878	NP_001260913.1	PKc_like	112..>286	CDD:304357
		SPS1	123..>284	CDD:223589
		SPS1	<491..756	CDD:223589	66/274 (24%)
		PKc_like	<517..652	CDD:304357	37/143 (26%)
C56C10.6	NP_495333.1	PKc_like	24..290	CDD:389743	46/186 (25%)
C56C10.6	NP_495333.1	CAF-1_p150	322..>407	CDD:371622	22/107 (21%)
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_KOG1164
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	0	0.000	Not matched by this tool.
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	1	0.900