Protein Alignment CG8878 and vrk-1

DIOPT Version :9

• Sequence 1: NP_001260913.1
• Gene: CG8878 / 36302
• FlyBaseID: FBgn0027504
• Length: 1004
• Species: Drosophila melanogaster
• Sequence 2: NP_495185.1
• Gene: vrk-1 / 174004
• WormBaseID: WBGene00017895
• Length: 610
• Species: Caenorhabditis elegans
• Alignment Length: 919
• Identity: 165/919 - (17%)
• Similarity: 284/919 - (30%)
• Gaps: 375/919 - (40%)

  Fly   100 RPVYTLRPSVVNGTILRDVLSKAWRLGRPIGKGNFGEIFLASDDTVCPASSETAKYVVKIEPHSN 164
            :.::.|...|..|..:.|:..|.:.:|:....|.||.|.      .|....::.:.|:||||.:|
 Worm     9 KKLHELAAEVRVGHKINDISKKTFIVGKQFATGGFGRIH------TCTEEGKSQQMVMKIEPSTN 67

  Fly   165 GPLFVEIHCLINTSRNNDLSDAAEDAASLPAPQTHVLSRGPPSGIPSFIASGTHYFGDVRYRFLV 229
            |||..|: .:.|.....:|.::.:....:..           .|:|..||:|...:...:.|:::
 Worm    68 GPLLTEV-VVFNRILKKELIESYKKKKKISW-----------IGLPYLIANGYFTYESEKMRYMI 120

  Fly   230 LPRFDRDLHSL--IKNSRVQQKSLLVLAVHIINVLENLHDKGYCHNDIKAQNLMVSKCKYLRRQV 292
            :|::...|.::  .....:..|..|.:|..|::.||.||:..|.|.|:||.|:::
 Worm   121 IPKYATSLEAVRETNGGTLAMKDSLTVASCILDALEYLHESDYAHADVKAANILL---------- 175

  Fly   293 VPKGNGYEDHYEEKQQTTDSGNSSEQETNDDDYFLKSEKFALKKIVDIKQDEDEDDEDFDDGATS 357
                        |||
 Worm   176 ------------EKQ-------------------------------------------------- 178

  Fly   358 NSNNSNSLDVFHTPVNKKRSARNAIQFSGSNPVRACRREKRNSMYEEMVKSHYLRPTKRISYREE 422
                    .|:.|.|
 Worm   179 --------GVYSTAV-------------------------------------------------- 185

  Fly   423 FNEDGYPKETAENSDESPESSDNESDEFIPPSSRRSVIKRGRSAQIATPKKTPVSTRASRQEKVK 487
                                                                             
 Worm   186 ----------------------------------------------------------------- 185

  Fly   488 KEPNGDQKLRSRGSKHLDNNPTEYKFLPTEEEHVFLIDFGLASKFQDRGVHRPFIMDQRRAHDGT 552
                                               |:|||||.: ....|.:|   |::|||:||
 Worm   186 -----------------------------------LVDFGLAHR-TTNNVDKP---DKKRAHNGT 211

  Fly   553 LEFTSRDAHLGAH-SRRSDLECLGYNLLYWSEGYLPWKDVAQQQQQEKVHRAKELFMTDVPEMLR 616
            ..|||.|||.|.: |.|.|:|.|.|||:.|:.|.|||  :|.:...|||..||:.|:..:|..|:
 Worm   212 CIFTSTDAHRGNNPSFRGDIEILAYNLMMWATGTLPW--MALESSPEKVFDAKQKFIAGLPGTLQ 274

  Fly   617 QFYGKQVPKYLG--EFLLQIGQLAYQERPNYERYRKIFKREYQRLGYDPCQMRLSSEEILRTCVS 679
            .....:....:|  ..:..|..     :.||.  .|:...:.::|..|..|
 Worm   275 NVLKNESSAVVGCIASMFDISM-----KTNYT--DKVDMGKLKKLVTDAIQ-------------- 318

  Fly   680 TKDVVDGSKCDIFELNNKAAVNVMRNSTLSTPFQEHSLT----NRVSPKNLRSKSNKKTTKKKFS 740
             |...||.|                     ||.::..|.    |.|:||    :|.::...|:
 Worm   319 -KTSSDGKK---------------------TPTRQKKLAEEDKNAVTPK----RSTRRLAVKE-- 355

  Fly   741 WAEVLSQDPDQIARERAVKEFEREETICPLESRLPRRYEGKPTYAILDMEQRRREKGLVVQEHIE 805
              |..::|.|::                          |.||       |::...:....::.:|
 Worm   356 --ESDNKDNDEV--------------------------EVKP-------EKKATPRKRTTRKAVE 385

  Fly   806 EEEEDADEDDEEENQEAM--------------DIDQEEDGEAADSAEGEDESDRSMEGSDCSDHS 856
            ...:..|.:::.||.::.              |:|.||:.....|:....:...|.||||.:..|
 Worm   386 VNNDSDDNEEQYENPKSKSSRTQTKSKRAKEEDVDDEEEIIIPKSSRSRSKVQLSGEGSDVTTPS 450

  Fly   857 QKRARGRPKGTSRKQTTSRQAQPHQNQPPVKVHRGVGRPGKN-SGVVKLAAGAVSKNRTTPLSAV 920
            ...:..|.:......|:|..:   .|:...|:.:...|...| |.:|.:.....|..  :|.::.
 Worm   451 SAASTSRSRSIRLGLTSSTAS---SNKVAKKIEQKYKRLSMNKSSLVPVTISVASDK--SPTTST 510

  Fly   921 ASNKRGCATRKENSTLASATGEGERKLKSGRTRRALYKTEPKHGEHDAENNSSLLVVQNLYGEYD 985
            .|:..|..:::::|   ...|||...........|:.|.:.|.|...| ..:|...::.:.|
 Worm   511 PSSSSGLRSKRKSS---EDVGEGITLKTQVLITPAIKKAKTKSGISSA-TKASPTELRRVPG--- 568

  Fly   986 DENNYGKGR 994
             ..|:.|||
 Worm   569 -VRNFPKGR 576

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
CG8878	NP_001260913.1	PKc_like	112..>286	CDD:304357	43/175 (25%)
		SPS1	123..>284	CDD:223589	40/162 (25%)
		SPS1	<491..756	CDD:223589	67/271 (25%)
		PKc_like	<517..652	CDD:304357	48/137 (35%)
vrk-1	NP_495185.1	STKc_VRK	26..312	CDD:270917	96/546 (18%)
		SPS1	32..415	CDD:223589	121/720 (17%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_KOG1164
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	1	1.050	204	1.000	Inparanoid score	I2444
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	1	1.100	-	-	O	PTHR11909
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	1	1.000	-	-
TreeFam	0	0.000	Not matched by this tool.
	5	4.960