Protein Alignment CG8878 and CSNK1E

DIOPT Version :9

• Sequence 1: NP_001260913.1
• Gene: CG8878 / 36302
• FlyBaseID: FBgn0027504
• Length: 1004
• Species: Drosophila melanogaster
• Sequence 2: NP_001885.1
• Gene: CSNK1E / 1454
• HGNCID: 2453
• Length: 416
• Species: Homo sapiens
• Alignment Length: 765
• Identity: 132/765 - (17%)
• Similarity: 203/765 - (26%)
• Gaps: 387/765 - (50%)

  Fly   123 WRLGRPIGKGNFGEIFLASDDTVCPASSETAKYVVKIEPHSNGPLFVEIHCLINTSRNNDLSDAA 187
            :||||.||.|:||:|:|.::    .||.|  :..:|:|            | :.|..
Human     9 YRLGRKIGSGSFGDIYLGAN----IASGE--EVAIKLE------------C-VKTKH-------- 46

  Fly   188 EDAASLPAPQTHVLSR-------GPPSGIPSFIASGTHYFGDVRYRFLVLPRFDRDLHSLIK--N 243
                    ||.|:.|:       |  .||||....|..  ||  |..:|:......|..|..  :
Human    47 --------PQLHIESKFYKMMQGG--VGIPSIKWCGAE--GD--YNVMVMELLGPSLEDLFNFCS 97

  Fly   244 SRVQQKSLLVLAVHIINVLENLHDKGYCHNDIKAQNLMVSKCKYLRRQVVPKGNGYEDHYEEKQQ 308
            .:...|::|:||..:|:.:|.:|.|.:.|.|:|..|.::...|        |||
Human    98 RKFSLKTVLLLADQMISRIEYIHSKNFIHRDVKPDNFLMGLGK--------KGN----------- 143

  Fly   309 TTDSGNSSEQETNDDDYFLKSEKFALKKIVDIKQDEDEDDEDFDDGATSNSNNSNSLDVFHTPVN 373
                                                                             
Human   144 ----------------------------------------------------------------- 143

  Fly   374 KKRSARNAIQFSGSNPVRACRREKRNSMYEEMVKSHYLRPTKRISYREEFNEDGYPKETAENSDE 438
                                                                             
Human   144 ----------------------------------------------------------------- 143

  Fly   439 SPESSDNESDEFIPPSSRRSVIKRGRSAQIATPKKTPVSTRASRQEKVKKEPNGDQKLRSRGSKH 503
                                                                             
Human   144 ----------------------------------------------------------------- 143

  Fly   504 LDNNPTEYKFLPTEEEHVFLIDFGLASKFQDRGVHRPFIMDQRRAHDGTLEFTSRDAHLG-AHSR 567
                            .|::||||||.|::|...|:.....:.:...||..:.|.:.||| ..||
Human   144 ----------------LVYIIDFGLAKKYRDARTHQHIPYRENKNLTGTARYASINTHLGIEQSR 192

  Fly   568 RSDLECLGYNLLYWSEGYLPWKDVAQQQQQEKVHRAKELFMTDVPEMLRQFYGKQVPKYLGEFLL 632
            |.|||.|||.|:|::.|.|||:.:....:::|..|..|..|:...|:|.:.|    |.....:|.
Human   193 RDDLESLGYVLMYFNLGSLPWQGLKAATKRQKYERISEKKMSTPIEVLCKGY----PSEFSTYLN 253

  Fly   633 QIGQLAYQERPNYERYRKIFKREYQRLGYDPCQMRLSSEEILRTCVSTKDVVDGSKCDIFELNNK 697
            ....|.:.::|:|...|::|:..:.|.|:                         |...:|:.|
Human   254 FCRSLRFDDKPDYSYLRQLFRNLFHRQGF-------------------------SYDYVFDWN-- 291

  Fly   698 AAVNVMRNSTLSTPFQEHSLTNRVSPKNLRSKSNKKTTKKKFSWAEVLSQDPDQIARERAVKEFE 762
                                                  ..||..|    ::|:.:.|||  :|.|
Human   292 --------------------------------------MLKFGAA----RNPEDVDRER--REHE 312

  Fly   763 REETICPLESRLPRRY-EGKPTYAILDMEQRRREKGLVVQEHIEEEEEDADEDDEEENQEAMDID 826
            |||.:..|.....|.. .|.||.|              ....:....|..........|.|
Human   313 REERMGQLRGSATRALPPGPPTGA--------------TANRLRSAAEPVASTPASRIQPA---- 359

  Fly   827 QEEDGEAADSAEGEDESDRSMEGSDCSDHSQKRARGRPKGTSRKQTTSRQ 876
                |..:..|....:.:|.:        |.:..||.|...|....|.||
Human   360 ----GNTSPRAISRVDRERKV--------SMRLHRGAPANVSSSDLTGRQ 397

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
CG8878	NP_001260913.1	PKc_like	112..>286	CDD:304357	46/171 (27%)
		SPS1	123..>284	CDD:223589	46/169 (27%)
		SPS1	<491..756	CDD:223589	55/265 (21%)
		PKc_like	<517..652	CDD:304357	44/135 (33%)
CSNK1E	NP_001885.1	STKc_CK1_delta_epsilon	8..282	CDD:271027	96/547 (18%)
		Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite	301..416		29/129 (22%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_KOG1164
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
User_Submission	0	0.000	Not matched by this tool.
	2	1.810