Protein Alignment CG8878 and Ttbk1

DIOPT Version :9

• Sequence 1: NP_001260913.1
• Gene: CG8878 / 36302
• FlyBaseID: FBgn0027504
• Length: 1004
• Species: Drosophila melanogaster
• Sequence 2: NP_001156336.1
• Gene: Ttbk1 / 106763
• MGIID: 2147036
• Length: 1308
• Species: Mus musculus
• Alignment Length: 1031
• Identity: 203/1031 - (19%)
• Similarity: 344/1031 - (33%)
• Gaps: 307/1031 - (29%)

  Fly   118 VLSKAWRLGRPIGKGNFGEIFLASD----DTVC--PASSETAKYVVKIEPHSNGPLFVEIHCLIN 176
            |:...|::.:.||.|.||||:.|.|    :.|.  ..|::..|.|:|:|.           .::.
Mouse    29 VVKDRWKVLKKIGGGGFGEIYEAMDLLTRENVALKVESAQQPKQVLKMEV-----------AVLK 82

  Fly   177 TSRNNDLSDAAEDAASLPAPQTHVLSRGPPSGIPSFIASGTHYFGDVRYRFLVLPRFDRDLHSLI 241
            ..:..|                ||.         .||..|.    :.::.::|:....|:|..|
Mouse    83 KLQGKD----------------HVC---------RFIGCGR----NEKFNYVVMQLQGRNLADL- 117

  Fly   242 KNSRVQQKSLLVLAV------HIINVLENLHDKGYCHNDIKAQNLMVS-------KCKYLRRQVV 293
              .|.|.:....|:.      .|:..:|.:|..|:.|.|||..|..:.       ||..|
Mouse   118 --RRSQPRGTFTLSTTLRLGKQILESIEAIHSVGFLHRDIKPSNFAMGRLPSTYRKCYML----- 175

  Fly   294 PKGNGYEDHYEEKQQTTDSGNSSEQETNDDDYFLKSEKFALKKIVDIKQDEDEDDEDFDDGATSN 358
                   |....:|.|..:|:  .:...:...|..:.::|     .:...::.:....||
Mouse   176 -------DFGLARQYTNTTGD--VRPPRNVAGFRGTVRYA-----SVNAHKNREMGRHDD----- 221

  Fly   359 SNNSNSLDVFHTPVNKKRSARNAIQFS-GSNPVRACRREKRNSMYEEMVKSHYL---RPTK---- 415
                 ...:|:.          .::|: |..|.|..:.:::..|.:|..:...|   .|::
Mouse   222 -----LWSLFYM----------LVEFAVGQLPWRKIKDKEQVGMIKEKYEHRMLLKHMPSEFHLF 271

  Fly   416 --RISYREEFNEDGYP--KETAENSDESPESSDNESDEF--------------IPPSSRRSVIKR 462
              .|:..:.|.:..|.  ....|||.:....::||:.::              .||...    .|
Mouse   272 LDHIASLDYFTKPDYQLIMSVFENSMKERGIAENEAFDWEKAGTDALLSTSTSTPPQQN----TR 332

  Fly   463 GRSAQIATPKKTPVS---TRASRQEKVKKEPNGDQK-----LRSRGSK------HLDNNPTEYKF 513
            ..:|.......|||.   .|.:.::.::.|...||:     |..|..:      ||..:|...:.
Mouse   333 QTAAMFGVVNVTPVPGDLLRENTEDVLQGEHLSDQENAPPILPGRPPEGLGPGPHLVPHPGGPEA 397

  Fly   514 LPTEEEHV----FLIDFG---LASKFQDRGVHRPF---------------IMDQRRAHDGTLE-- 554
            ...||..|    ..|:.|   ...:.|.|||..|.               .:..||.:....|
Mouse   398 EVWEETDVNRNKLRINIGKTPCVEEEQSRGVGVPSSPVRAPPDSPTTPVRSLCYRRVNSPESERL 462

  Fly   555 FTSRDAHLGAHSRRSDLECLG-----------YNLLYWSEGYLPWK-----DVAQQQQQEKVHRA 603
            .|:.|..:....|||.::..|           ..:|....|:...:     ||:...:||.:..|
Mouse   463 STAADGRVELQERRSRMDLPGSPSRQACSSQPAQMLSVDTGHADRQASGRMDVSASVEQEALSNA 527

  Fly   604 --------------KELFMTDVPEMLRQFYGKQVPKYLGEFLLQIGQLAYQERPNYERYRKIFKR 654
                          ||..:.|....|:.|.....|...|         ...|.|...|.......
Mouse   528 FRSVPLAEEEDFDSKEWVIIDKETELKDFPPGAEPSTSG---------TTDEEPEELRPLPEEGE 583

  Fly   655 EYQRLGYDPC------QMRLSSEEILRTCVSTKDVVDGSKCDIFELNNKAAVNVMRNSTLSTP-- 711
            |.:|||.:|.      .|...:||..|..:........|:.|            .|:.|...|
Mouse   584 ERRRLGTEPTVRPRGRGMHTLTEEDPRQMLPQPAPPQLSQAD------------GRSETSQPPTP 636

  Fly   712 -FQEHSLTNRVSPKNLRSKSNKKTTKKK-FSWAEVLSQD--PDQIARERAVKEFEREETICPLES 772
             ...||..:. .|:..|.:|:....::: ||.|.....:  |..:......::|:|:.:.....:
Mouse   637 GSPSHSPLHS-GPRPRRRESDPTGPQRQVFSVAPPFEVNGLPRAVPLALPYQDFKRDLSDYRERA 700

  Fly   773 RLPRRYE---------GKPTYAILDME-QRRREKGLVVQEHIEEEEEDADEDDEEENQEAMDIDQ 827
            ||..|..         ..|...:...: |...::|...:|..|||||:.:|::|||.:|..:.::
Mouse   701 RLLNRVRRVGFSHMLLTAPQVPLAPFQPQANGKEGEEEEEEEEEEEEEEEEEEEEEEEEEEEEEE 765

  Fly   828 EED----GE-----AADSAEGEDES-DRSMEG--SDCSDHSQKRARGRPK--------------- 865
            ||:    ||     :..|:||.:.| :||.||  |......||.||||..
Mouse   766 EEEAGALGEVLGPRSGSSSEGSERSTERSQEGAPSTLLADDQKEARGRASMADGDLEPEEGSKTL 830

  Fly   866 -----GTSRKQTTSRQAQP-------------HQNQPPVKVHRGVGRPGKNSGVVK--------- 903
                 |..:|...:.:..|             |:...|......|..||..|.::|
Mouse   831 VLVSPGDMKKSPVTAELAPDPDLGTLAALTPQHERPQPTGSQLDVSEPGTLSSILKSEPKPSGPG 895

  Fly   904 -------LAAGAVSKNRTTPLSAVASNKRGCATRKENSTLASATGEGER--KLKSG 950
                   :|.||.....|:|.:.|.......| .|.:..:.|:.|:..|  :|.:|
Mouse   896 AGGGVGLVAPGAGVTAVTSPFTKVERTFVHIA-EKSHLNVMSSGGQASRPEELSTG 950

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
CG8878	NP_001260913.1	PKc_like	112..>286	CDD:304357	40/186 (22%)
		SPS1	123..>284	CDD:223589	38/179 (21%)
		SPS1	<491..756	CDD:223589	66/341 (19%)
		PKc_like	<517..652	CDD:304357	36/188 (19%)
Ttbk1	NP_001156336.1	STKc_TTBK1	33..294	CDD:271032	61/342 (18%)
		PHA03307	324..>683	CDD:223039	75/384 (20%)
		Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite	364..397		7/32 (22%)
		Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite	418..448		5/29 (17%)
		Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite	474..671		43/218 (20%)
		Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite	720..899		42/178 (24%)
		PHA03307	963..>1305	CDD:223039
		Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite	985..1085
		Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite	1097..1308

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_KOG1164
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	0	0.000	Not matched by this tool.
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	1	0.900