Protein Alignment bsd and TPTEP2-CSNK1E

DIOPT Version :10

• Sequence 1: NP_610733.1
• Gene: bsd / 36302
• FlyBaseID: FBgn0027504
• Length: 1004
• Species: Drosophila melanogaster
• Sequence 2: NP_001276841.1
• Gene: TPTEP2-CSNK1E / 102800317
• HGNCID: 53829
• Length: 416
• Species: Homo sapiens
• Alignment Length: 765
• Identity: 132/765 - (17%)
• Similarity: 203/765 - (26%)
• Gaps: 387/765 - (50%)

  Fly   123 WRLGRPIGKGNFGEIFLASDDTVCPASSETAKYVVKIEPHSNGPLFVEIHCLINTSRNNDLSDAA 187
            :||||.||.|:||:|:|.::    .||.|  :..:|:|            | :.|..
Human     9 YRLGRKIGSGSFGDIYLGAN----IASGE--EVAIKLE------------C-VKTKH-------- 46

  Fly   188 EDAASLPAPQTHVLSR-------GPPSGIPSFIASGTHYFGDVRYRFLVLPRFDRDLHSLIK--N 243
                    ||.|:.|:       |  .||||....|..  ||  |..:|:......|..|..  :
Human    47 --------PQLHIESKFYKMMQGG--VGIPSIKWCGAE--GD--YNVMVMELLGPSLEDLFNFCS 97

  Fly   244 SRVQQKSLLVLAVHIINVLENLHDKGYCHNDIKAQNLMVSKCKYLRRQVVPKGNGYEDHYEEKQQ 308
            .:...|::|:||..:|:.:|.:|.|.:.|.|:|..|.::...|        |||
Human    98 RKFSLKTVLLLADQMISRIEYIHSKNFIHRDVKPDNFLMGLGK--------KGN----------- 143

  Fly   309 TTDSGNSSEQETNDDDYFLKSEKFALKKIVDIKQDEDEDDEDFDDGATSNSNNSNSLDVFHTPVN 373
                                                                             
Human   144 ----------------------------------------------------------------- 143

  Fly   374 KKRSARNAIQFSGSNPVRACRREKRNSMYEEMVKSHYLRPTKRISYREEFNEDGYPKETAENSDE 438
                                                                             
Human   144 ----------------------------------------------------------------- 143

  Fly   439 SPESSDNESDEFIPPSSRRSVIKRGRSAQIATPKKTPVSTRASRQEKVKKEPNGDQKLRSRGSKH 503
                                                                             
Human   144 ----------------------------------------------------------------- 143

  Fly   504 LDNNPTEYKFLPTEEEHVFLIDFGLASKFQDRGVHRPFIMDQRRAHDGTLEFTSRDAHLG-AHSR 567
                            .|::||||||.|::|...|:.....:.:...||..:.|.:.||| ..||
Human   144 ----------------LVYIIDFGLAKKYRDARTHQHIPYRENKNLTGTARYASINTHLGIEQSR 192

  Fly   568 RSDLECLGYNLLYWSEGYLPWKDVAQQQQQEKVHRAKELFMTDVPEMLRQFYGKQVPKYLGEFLL 632
            |.|||.|||.|:|::.|.|||:.:....:::|..|..|..|:...|:|.:.|    |.....:|.
Human   193 RDDLESLGYVLMYFNLGSLPWQGLKAATKRQKYERISEKKMSTPIEVLCKGY----PSEFSTYLN 253

  Fly   633 QIGQLAYQERPNYERYRKIFKREYQRLGYDPCQMRLSSEEILRTCVSTKDVVDGSKCDIFELNNK 697
            ....|.:.::|:|...|::|:..:.|.|:                         |...:|:.|
Human   254 FCRSLRFDDKPDYSYLRQLFRNLFHRQGF-------------------------SYDYVFDWN-- 291

  Fly   698 AAVNVMRNSTLSTPFQEHSLTNRVSPKNLRSKSNKKTTKKKFSWAEVLSQDPDQIARERAVKEFE 762
                                                  ..||..|    ::|:.:.|||  :|.|
Human   292 --------------------------------------MLKFGAA----RNPEDVDRER--REHE 312

  Fly   763 REETICPLESRLPRRY-EGKPTYAILDMEQRRREKGLVVQEHIEEEEEDADEDDEEENQEAMDID 826
            |||.:..|.....|.. .|.||.|              ....:....|..........|.|
Human   313 REERMGQLRGSATRALPPGPPTGA--------------TANRLRSAAEPVASTPASRIQPA---- 359

  Fly   827 QEEDGEAADSAEGEDESDRSMEGSDCSDHSQKRARGRPKGTSRKQTTSRQ 876
                |..:..|....:.:|.:        |.:..||.|...|....|.||
Human   360 ----GNTSPRAISRVDRERKV--------SMRLHRGAPANVSSSDLTGRQ 397

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
bsd	NP_610733.1	Protein Kinases, catalytic domain	112..>286	CDD:473864	46/171 (27%)
		Protein Kinases, catalytic domain	<517..652	CDD:473864	44/135 (33%)
TPTEP2-CSNK1E	NP_001276841.1	STKc_CK1_delta_epsilon	8..282	CDD:271027	96/547 (18%)