Protein Alignment INS and Ilp3

DIOPT Version :10

• Sequence 1: NP_000198.1
• Gene: INS / 3630
• HGNCID: 6081
• Length: 110
• Species: Homo sapiens
• Sequence 2: NP_648360.2
• Gene: Ilp3 / 39151
• FlyBaseID: FBgn0044050
• Length: 120
• Species: Drosophila melanogaster
• Alignment Length: 122
• Identity: 31/122 - (25%)
• Similarity: 51/122 - (41%)
• Gaps: 21/122 - (17%)

Human     1 MALWMR------LLPLLALLALWGPDPAAAFVNQHLCGSHLVEALYLVCGERGFFYTPKTRREAE 59
            |.:.||      |||.|.||.|.   .........|||..|.|.|..:|   .:.:...|:|..:
  Fly     1 MGIEMRCQDRRILLPSLLLLILM---IGGVQATMKLCGRKLPETLSKLC---VYGFNAMTKRTLD 59

Human    60 DLQVGQVELGGGPGAGSLQPLALEGSLQ-------KRGIVEQCCTSICSLYQLENYC 109
            .:...|::  |......|:.|..:.|:|       :.|:.::||...|::.::..||
  Fly    60 PVNFNQID--GFEDRSLLERLLSDSSVQMLKTRRLRDGVFDECCLKSCTMDEVLRYC 114

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
INS	NP_000198.1	IlGF_insulin_like	26..110	CDD:239833	21/91 (23%)
Ilp3	NP_648360.2	IlGF_insulin_bombyxin_like	33..114	CDD:239832	19/85 (22%)