DRSC - DRSC Integrative Ortholog Prediction Tool

back to: DIOPT - Ortholog Prediction Tool / DIOPT for Diseases and Traits

Protein Alignment Smyd4-4 and TPR9

DIOPT Version :9

Sequence 1:	NP_610730.1	Gene:	Smyd4-4 / 36299	FlyBaseID:	FBgn0027495	Length:	573	Species:	Drosophila melanogaster
Sequence 2:	NP_001321056.1	Gene:	TPR9 / 840233	AraportID:	AT1G33400	Length:	810	Species:	Arabidopsis thaliana

Alignment Length:	534	Identity:	118/534 - (22%)
Similarity:	200/534 - (37%)	Gaps:	145/534 - (27%)

- Green bases have known domain annotations that are detailed below.

  Fly    64 CNKR---SVEFRMLGNEQFSLKNRNYFQALELYNKSICYA-----EPNSEHLSIGYANRSAVLFE 120
            |.|.   |::.:..||..|  ::|::.:||.||:|::..|     :.:...|:..:.||:.||..
plant    68 CGKNEETSLDLKRRGNHCF--RSRDFDEALRLYSKALRVAPLDAIDGDKSLLASLFLNRANVLHN 130

  Fly   121 ------------------------WKRYRQ-----CLDNIKLA-RQANYPARLSHKL---DKRER 152
                                    |  ||:     .|.|.|.| |.......|...|   .:.:.
plant   131 LGLLKESLRDCHRALRIDPYYAKAW--YRRGKLNTLLGNYKDAFRDITVSMSLESSLVGKKQLQN 193

  Fly   153 DCQQLLDQQPPDVVPY-EFKLSFE------PHAQVPFIADCLELRETAAEGRFVVTNRDLAVGDL 210
            :.:.:.|.|....:.: |::.|.:      |..|:.....|:..:|   :||.:|:..|:....:
plant   194 ELKAIPDYQNNQTLEHDEYRPSNDAGVDHLPSVQMEVKLRCVSTKE---KGRGMVSECDIEEASV 255

  Fly   211 VSVEEPFCSTLLTPMRYIRCATCKRENYLTLIPCDSCCSTMFCSEECK--------SIAMQTYHR 267
            :.|||||...:....|...|..|..|.....:||.||...::|||.|:        :..|..:|.
plant   256 IHVEEPFSVVISKSCRETHCHFCLNELPADTVPCPSCSIPVYCSESCQIQSGGMLSTNEMDKHHI 320

  Fly   268 YE-CP--IIDFLNRMFN-KIHCIALRTTLVALN-----------IFPS--------IEELIDFCE 309
            :: .|  |::.:..:.: .|:..|  |.|:..:           :.||        |.:||
plant   321 FQKLPDDIVEHIKGVTSADIYYFA--TDLIQEHQHECRGANWPAVLPSDAVLAGRIIMKLI---- 379

  Fly   310 QEQNQDKCAFDLN-----------YNELTPEEHYRAIHGLVTNQHLRSV--------SDLFQRSV 355
               ||.|.|.||:           |:::.||.....        ||.|:        |.....||
plant   380 ---NQGKAATDLSNLQEILELSHTYSKMNPENKLEL--------HLLSIVLIWCLSKSSCPNLSV 433

  Fly   356 VCAVLKHFIIEYTPVKEYLGGEEGVNFFTDLLFRHLQTS-------PS-NMHGIDLVEQVNETKD 412
            ..|.:...||..:.:|        ||   .:....:::|       || |:...:.::.:.:.:.
plant   434 CEASVTQTIILLSQIK--------VN---SIAVARMKSSGDSFKCLPSGNISTKEPIQSLEQIRV 487

  Fly   413 DQTHSSGAYAFLSLINHSCAPNTVRIYEGTKAYMFVLRPIKAGNVLYDNYGAHFAICSKEQRLKR 477
            .|    ..|...||.||||.||....:......|.....:..|..|..:||........:.|::.
plant   488 GQ----ALYKTGSLFNHSCKPNIHLYFLSRGLIMQTTEFVPTGCPLELSYGPEVGKWDCKNRIRF 548

  Fly   478 LSLQYRFDCKCEGC 491
            |..:|.|.|:|.||
plant   549 LEEEYFFHCRCRGC 562

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
Smyd4-4	NP_610730.1	TPR_11	67..138	CDD:290150	24/108 (22%)
		zf-MYND	230..270	CDD:280009	13/48 (27%)
		SET	363..463	CDD:279228	22/107 (21%)
TPR9	NP_001321056.1	None

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Domainoid	1	1.000	61	1.000	Domainoid score	I3824
eggNOG	1	0.900	-	-		E2759_KOG2084
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	1	1.010	-	-		D1278034at2759
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	1	1.000	-	-		otm3360
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
SonicParanoid	1	1.000	-	-		X497
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	6	5.820