Protein Alignment Smyd4-4 and smyd4

DIOPT Version :9

• Sequence 1: NP_610730.1
• Gene: Smyd4-4 / 36299
• FlyBaseID: FBgn0027495
• Length: 573
• Species: Drosophila melanogaster
• Sequence 2: XP_012812690.1
• Gene: smyd4 / 779741
• XenbaseID: XB-GENE-945037
• Length: 777
• Species: Xenopus tropicalis
• Alignment Length: 562
• Identity: 137/562 - (24%)
• Similarity: 238/562 - (42%)
• Gaps: 105/562 - (18%)

  Fly    14 LQDWK---------LIGIISGKFNELKENHRKVDFVMRALI------DFKYIEKIFLNVTLREDK 63
            :|:|:         |......||:.:.:    :|.:.:|.:      :.:.||::..|||:.:|
 Frog    43 VQEWQDQAQSIWAHLTSSEKEKFSSIAD----LDEIFQACLSHLQQDEEQLIERLCCNVTVAKD- 102

  Fly    64 CNKRSVE-FRMLGNEQFSLKNRNYFQALELYNKSICYAEPNSEHLSIGYANRSAVLFEWKRYRQC 127
              ..:|: |:..||::|:  .:.|..|..||:|:|.:|:..||.|::.:|||||.||...:|..|
 Frog   103 --PNAVQFFKEEGNKRFA--EKQYATAAGLYSKAISHAKSGSEALAVCFANRSAALFYLGQYSVC 163

  Fly   128 LDNIKLARQANYPARLSHKLDKRERDCQQLLDQQPPDVVP---------------------YEFK 171
            |::|:.|:...||.||.:|:.:|:.:|.|.| ::|....|                     .|..
 Frog   164 LEDIQHAQDHGYPERLRNKILQRKAECFQRL-RKPSSCDPKLECVETVKPKKEPQTSTERLKEMA 227

  Fly   172 LSFEPHAQVPFIADC-LELRETAAEGRFVVTNRDLAVGDLVSVEEPFCSTLLTPMRYIR------ 229
            |...||..   .|.| |.|.....:||.::.::::..|:::..||.|.|.::...:..|
 Frog   228 LDRNPHIT---NASCALHLNFDTRKGRHLLASQNIEQGEVLIWEEAFASVIIPERKQWRKEIKWD 289

  Fly   230 ---------CATCKRENYLTLIPCDSCCSTMFCSEECKSIAMQTYHRYECPIIDFLNRMFNKIHC 285
                     |..| ....:..:||..|....:||:||...|.::||..||.:.|.|..:....|
 Frog   290 TRITACDHYCHYC-LNRVIASLPCQYCSFARYCSQECMDKAWRSYHYIECSMGDLLLALGMFCH- 352

  Fly   286 IALRTTLVA-LNIFPSIEELIDFCEQEQNQDKCAFDLNYNELTPEEHYRAIHGLV--TNQHLR-- 345
            .|||..||| ..:|....|.....:.......|.....|:|..... |:::..|:  |..|..
 Frog   353 TALRAVLVAGCRLFSQSLEQTGSADATDKTKVCNSKNTYHEKYCSS-YQSVVNLLPHTENHPAER 416

  Fly   346 ------SVSDLFQRSVVCAVL-KHFIIEYTPVKEYLGGEEGV--------NFFTDLLFRHLQTSP 395
                  :.:.|:::  :|.:: |..:...:..::.|..|.|.        .|....:.||:....
 Frog   417 KFLCGLTAAALYKK--LCLIMAKDLVSSTSQTEKSLTKESGTIEDWSSVRQFLGPTVLRHMLQLY 479

  Fly   396 SNMHGIDLVEQVNETKDDQTHS-----------SGAYAFLSLINHSCAPNTVRIYEGTKAYMFVL 449
            .|...:..::   |.:|:.:.|           :..:..|||:||||.|||...:.|....:...
 Frog   480 CNAQAVTALQ---ENEDESSLSLVKSNKSIRLATAVFPVLSLLNHSCDPNTTVSFTGRFVTVRAN 541

  Fly   450 RPIKAGNVLYDNYGAHFAICSKEQRLKRLSLQYRFDCKCEGC 491
            |||:....:...||.|.......:|.:.|..||.|.|:|:.|
 Frog   542 RPIRRDEEVTHCYGPHKLRMDVAERQQLLKDQYFFVCQCKAC 583

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Smyd4-4	NP_610730.1	TPR_11	67..138	CDD:290150	27/71 (38%)
		zf-MYND	230..270	CDD:280009	12/39 (31%)
		SET	363..463	CDD:279228	24/118 (20%)
smyd4	XP_012812690.1	TPR repeat	106..134	CDD:276809	10/29 (34%)
		TPR_11	107..170	CDD:290150	25/64 (39%)
		TPR repeat	143..173	CDD:276809	13/29 (45%)
		zf-MYND	299..338	CDD:280009	12/39 (31%)
		SET	<509..555	CDD:279228	14/45 (31%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	1	1.000	73	1.000	Domainoid score	I9074
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	1	1.010	-	-		D1278034at2759
OrthoFinder	1	1.000	-	-		FOG0000542
OrthoInspector	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	1	1.030	-	avgDist	Average_Evolutionary_Distance	R5130
SonicParanoid	1	1.000	-	-		X497
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	6	5.950