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Protein Alignment Smyd4-4 and SMYD3

DIOPT Version :9

Sequence 1:	NP_610730.1	Gene:	Smyd4-4 / 36299	FlyBaseID:	FBgn0027495	Length:	573	Species:	Drosophila melanogaster
Sequence 2:	NP_001161212.1	Gene:	SMYD3 / 64754	HGNCID:	15513	Length:	428	Species:	Homo sapiens

Alignment Length:	333	Identity:	75/333 - (22%)
Similarity:	116/333 - (34%)	Gaps:	108/333 - (32%)

- Green bases have known domain annotations that are detailed below.

  Fly   192 TAAEGRFVVTNRDLAVGDLVSVEEPFCSTLLTPMRYIRCATC--KRENYLTLIPCDSCCSTMFCS 254
            ||..|..:.....|..|:|:...:|...|:....|.:.|..|  .:|.   |:.|..|....:||
Human    11 TAKRGNGLRAVTPLRPGELLFRSDPLAYTVCKGSRGVVCDRCLLGKEK---LMRCSQCRVAKYCS 72

  Fly   255 EECKSIAMQTYHRYECPIIDFLN--------RMFNKIHCIALRTTLVALNIFPSIEELIDFCEQE 311
            .:|:..|... |:.||..:....        |:..::                 :.:|:|....|
Human    73 AKCQKKAWPD-HKRECKCLKSCKPRYPPDSVRLLGRV-----------------VFKLMDGAPSE 119

  Fly   312 QNQDKCAFDL--NYNELTPEEHYRAIHGLV-TNQH-----------LRSVSDLFQ--RSVVCAVL 360
            ..:....:||  |.|:|| |:....:..|| |.||           |....|||:  ..|:|
Human   120 SEKLYSFYDLESNINKLT-EDKKEGLRQLVMTFQHFMREEIQDASQLPPAFDLFEAFAKVIC--- 180

  Fly   361 KHFIIEYTPVKEYLGGEEGVNFFTDLLFRHLQTSPSNMHGIDLVEQVNETKDDQTHSSGAYAFLS 425
                                |.||        ...:.|..:.:               |.|..:|
Human   181 --------------------NSFT--------ICNAEMQEVGV---------------GLYPSIS 202

  Fly   426 LINHSCAPNTVRIYEGTKAYMFVLRPIKAGNVLYDNYGAHFAIC------SKEQRLKRLSLQYRF 484
            |:||||.||...::.|....:..:|.|:.|..|        .||      :.|:|.|:|..||.|
Human   203 LLNHSCDPNCSIVFNGPHLLLRAVRDIEVGEEL--------TICYLDMLMTSEERRKQLRDQYCF 259

  Fly   485 DCKCEGCE 492
            :|.|..|:
Human   260 ECDCFRCQ 267

Known Domains:

Indicated by green bases in alignment.

Software error:

Illegal division by zero at /www/www.flyrnai.org/docroot/cgi-bin/DRSC_prot_align.pl line 591.

For help, please send mail to the webmaster (ritg@hms.harvard.edu), giving this error message and the time and date of the error.