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Protein Alignment Smyd4-4 and SMYD2

DIOPT Version :9

Sequence 1:	NP_610730.1	Gene:	Smyd4-4 / 36299	FlyBaseID:	FBgn0027495	Length:	573	Species:	Drosophila melanogaster
Sequence 2:	NP_064582.2	Gene:	SMYD2 / 56950	HGNCID:	20982	Length:	433	Species:	Homo sapiens

Alignment Length:	456	Identity:	98/456 - (21%)
Similarity:	152/456 - (33%)	Gaps:	147/456 - (32%)

- Green bases have known domain annotations that are detailed below.

  Fly   195 EGRFVVTNRDLAVGDLVSVEEPFCSTLLTPMRYIRCATC--KRENYLTLIPCDSCCSTMFCSEEC 257
            :||.:...:...||||:.....:...|....|...|..|  ::|.   |..|..|....:|:.||
Human    17 KGRGLRALQPFQVGDLLFSCPAYAYVLTVNERGNHCEYCFTRKEG---LSKCGRCKQAFYCNVEC 78

  Fly   258 KSIAMQTYHRYEC-PIIDFLNRMFNKIHCIALRTTLVA-LNIFPSIEELIDFCEQEQNQDKCAFD 320
            :. .....|:.|| |::.| ...:|....:.|...::| ..|.|
Human    79 QK-EDWPMHKLECSPMVVF-GENWNPSETVRLTARILAKQKIHP--------------------- 120

  Fly   321 LNYNELTPEEHYRAIHGLVTNQHLRSV----SDLFQRSVVCAVLKHFIIEYTPVKEYLGGEEGVN 381
                |.||.|...|:...  ..||..:    .||.|..:  |.|.||      ..::||
Human   121 ----ERTPSEKLLAVKEF--ESHLDKLDNEKKDLIQSDI--AALHHF------YSKHLG------ 165

  Fly   382 FFTDLLFRHLQTSPSNMHGIDLVEQVN----ETKDDQTHSSGAYAF--LSLINHSCAPNTVRIYE 440
                        .|.|...:.|..|||    ..:|::....|:..|  ::|:||||.||.:..|:
Human   166 ------------FPDNDSLVVLFAQVNCNGFTIEDEELSHLGSAIFPDVALMNHSCCPNVIVTYK 218

  Fly   441 GTKAYMFVLRPIKAGNVLYDNYGAHFAICSKEQRLKRLSLQYRFDCKCEGC-------------E 492
            ||.|.:..::.||.|..::.:|  ...:...|.|..||...|.|.|:|:.|             :
Human   219 GTLAEVRAVQEIKPGEEVFTSY--IDLLYPTEDRNDRLRDSYFFTCECQECTTKDKDKAKVEIRK 281

  Fly   493 LNYP------------------MFGMMPHKATVPSVTDDTELALSSYNYDFAVSN---------- 529
            |:.|                  .|....|..:...:.:..||:....:..|..||
Human   282 LSDPPKAEAIRDMVRYARNVIEEFRRAKHYKSPSELLEICELSQEKMSSVFEDSNVYMLHMMYQA 346

  Fly   530 -----YRKYCDFLTQYGD--------DYP-------------------CEQISSAEECLKMALHI 562
                 |.:..:...|||.        .||                   .|..::.|:.||.|:.|
Human   347 MGVCLYMQDWEGALQYGQKIIKPYSKHYPLYSLNVASMWLKLGRLYMGLEHKAAGEKALKKAIAI 411

  Fly   563 M 563
            |
Human   412 M 412

Known Domains:

Indicated by green bases in alignment.

Software error:

Illegal division by zero at /www/www.flyrnai.org/docroot/cgi-bin/DRSC_prot_align.pl line 591.

For help, please send mail to the webmaster (ritg@hms.harvard.edu), giving this error message and the time and date of the error.