DRSC/TRiP Functional Genomics Resources

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Protein Alignment Smyd4-4 and SmydA-2

DIOPT Version :9

Sequence 1:NP_610730.1 Gene:Smyd4-4 / 36299 FlyBaseID:FBgn0027495 Length:573 Species:Drosophila melanogaster
Sequence 2:NP_649084.1 Gene:SmydA-2 / 40075 FlyBaseID:FBgn0036839 Length:530 Species:Drosophila melanogaster


Alignment Length:461 Identity:104/461 - (22%)
Similarity:157/461 - (34%) Gaps:147/461 - (31%)


- Green bases have known domain annotations that are detailed below.


  Fly   186 CLELRETAAEGRFVVTNRDLAVGDLVSVEEPFC---STLLTPMRYIRCATCKRE---------NY 238
            |.|:......||.:...||:.:|:.:..|.|..   .....|:    |..|.|.         ||
  Fly    48 CFEIATNEVLGRHLRATRDIKIGEQILKEAPLVLGPKVASAPL----CLGCHRNLLAPGKPRGNY 108

  Fly   239 LTLIPCDSCCSTMFCSEECKSIAMQTYHRYECPIIDFLNRMFNKIHCIALRTTLVALNIFPSIEE 303
               ..|.| ||...|.:||:.   ..:|:.||.::...|  |..           .:|..|..||
  Fly   109 ---HKCSS-CSWPLCGKECED---SVHHKAECQLMSGSN--FQS-----------KINYVPGEEE 153

  Fly   304 ---------LIDFCEQEQNQDKCAFDLNYNELTPEEHYRAIHGLVTNQHLRSVSDLFQRSVVCAV 359
                     ::..|...:::|..||...||   .|:|.:.          |..:.|:|      |
  Fly   154 RKESAYCVIMLLRCMHLKDKDPDAFLKLYN---LEDHLKE----------RLETPLYQ------V 199

  Fly   360 LKHFIIEYTPVKEYLGGEEGVNFFTDLLFRHLQTSPSNMHGIDLVEQVNETKDDQTHSSGAYAFL 424
            |:..:|.:  :|..||.::........:...|.|:...      |.|..|.:..:....||    
  Fly   200 LRANLITF--IKTVLGMKDWPEMDILRIAAILDTNTFE------VRQPRERRKIRALYPGA---- 252

  Fly   425 SLINHSCAPNTVRIYEGTKAYMFVL-RPIKAGNVLYDNYGAHFAICSKEQRLKRLSLQYRFDCKC 488
            ::|:|.|.||....::.....:|:. |.|..|.:|..:|..  .:.|..||...|.....|||.|
  Fly   253 AMISHDCVPNMRHRFDDDMNIVFLAKRKIAKGEILSISYTQ--PLRSTIQRRVHLRQAKCFDCSC 315

  Fly   489 EGCE------------------------LNYPMFGMMPHKATVPS--------VTDDTEL----- 516
            ..|:                        || |:....|.|..:.:        ||.|.||     
  Fly   316 ARCQDPEELGSFAGAQTCLKCKAGKIISLN-PLLNSAPWKCQLCNFKRSAKDVVTSDAELQQELE 379

  Fly   517 --------ALSSYNY----DFAVSN----YRKYCDFLTQ-YGD--DYPCEQISS---------AE 553
                    ||..:.|    |...:|    ..||.  ||| ||.  .:..|::|.         .|
  Fly   380 SLDKTTPVALEEFIYRHRADLHETNTHILQAKYA--LTQLYGSAPGFAMEELSGESLNRKLQLCE 442

  Fly   554 ECLKMA 559
            |.||:|
  Fly   443 ELLKLA 448

Known Domains:


Indicated by green bases in alignment.

GeneSequenceDomainRegion External IDIdentity
Smyd4-4NP_610730.1 TPR_11 67..138 CDD:290150
zf-MYND 230..270 CDD:280009 13/48 (27%)
SET 363..463 CDD:279228 21/100 (21%)
SmydA-2NP_649084.1 zf-MYND 9..46 CDD:280009
SET <246..291 CDD:214614 12/48 (25%)
Blue background indicates that the domain is not in the aligned region.


Information from Original Tools:


Tool Simple Score Weighted Score Original Tool Information
BLAST Result Score Score Type Cluster ID
Compara 00.000 Not matched by this tool.
Domainoid 00.000 Not matched by this tool.
eggNOG 1 0.900 - - E2759_KOG2084
Homologene 00.000 Not matched by this tool.
Inparanoid 00.000 Not matched by this tool.
Isobase 00.000 Not matched by this tool.
OMA 00.000 Not matched by this tool.
OrthoDB 00.000 Not matched by this tool.
OrthoFinder 00.000 Not matched by this tool.
OrthoInspector 00.000 Not matched by this tool.
orthoMCL 00.000 Not matched by this tool.
Panther 00.000 Not matched by this tool.
Phylome 1 0.910 - -
RoundUp 00.000 Not matched by this tool.
SonicParanoid 00.000 Not matched by this tool.
21.810

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