Protein Alignment Smyd4-4 and Smyd4-2

DIOPT Version :9

• Sequence 1: NP_610730.1
• Gene: Smyd4-4 / 36299
• FlyBaseID: FBgn0027495
• Length: 573
• Species: Drosophila melanogaster
• Sequence 2: NP_648574.1
• Gene: Smyd4-2 / 39414
• FlyBaseID: FBgn0036282
• Length: 663
• Species: Drosophila melanogaster
• Alignment Length: 576
• Identity: 140/576 - (24%)
• Similarity: 225/576 - (39%)
• Gaps: 136/576 - (23%)

  Fly     1 MDVYDVSDDLIKKLQDWKLIGIISGKFNELKENHRKV--DFVMRALID-----FKYIEKIF---- 54
            :||.|...|  |.|:::         |.:||.|..:|  .|..|.:.|     .::::.:|
  Fly    29 VDVRDACGD--KWLRNY---------FGKLKSNAARVLSIFSDREVCDPVLGVLEHVQPVFKQKD 82

  Fly    55 -LNVTLREDKCNKRSVEFRMLGNEQFSLKNRNYFQALELYNKSICYA-EPNSE-------HLSIG 110
             |....|..:.:|.   :.|.|:...........|||...|.::..| :.|::       .|::.
  Fly    83 ALFSAQRRAQADKL---YLMSGSGDGEESRELLQQALMAANLAVMRAPDRNADPVLDEGLTLALA 144

  Fly   111 YANRSAVLFEWKRYRQCLDNIKLA--------RQANY-------------PAR--LSHKLDKRER 152
            |.:|:::|.........|:::|||        ...:|             |||  :|.|:.::..
  Fly   145 YRSRASILIRLGEGEAALNDLKLAINFGLELKSSVDYYLKMAKAYAVMGEPARAEISLKIAEKMP 209

  Fly   153 DCQ----QLLDQQPPDVVPYEFKLSFEPHAQVPFIA-----------DCLELRETAAEGRFVVTN 202
            .|.    .|..::...|.|...:.:.|   |||.:|           ..:.|.||..:|||||.|
  Fly   210 GCDATHIALCRKELSSVKPKPKEATSE---QVPQLAHGESAELVGASKVVRLVETKDKGRFVVAN 271

  Fly   203 RDLAVGDLVSVEEPFCSTLLTPMRYIRCATCKRENYLTLIPCDSCCSTMFCSEECKSIAMQTYHR 267
            ..|..||::..|||..:.|........|..|.:..: |.:.|..|....|||.:|...|..:|||
  Fly   272 EGLRTGDVLLFEEPVAACLEPSYFGTHCHHCFKRLH-TPVSCLHCSGIAFCSAQCMGEACSSYHR 335

  Fly   268 YECPIIDFLNRMFNKIHCIALRTTLVALNIF---PSIEELIDFCEQEQNQDKCAFDLNYNELTPE 329
            :||..:|.:......|.|      .:||.||   ||:|           |.....:|.:
  Fly   336 FECEYMDLMIGSGMSILC------FIALRIFTQAPSLE-----------QGLATANLLF------ 377

  Fly   330 EHYRAIHGLVTNQHLRSVSDLFQRSVVCAVLKHFIIEYTPVKEYLGGE--EGVN------FFTDL 386
            ||      |.:::..|...|..:|    |::..|::.......|.|..  ||||      .....
  Fly   378 EH------LCSHEEDRQPDDYLRR----ALMSGFLLRILQKSLYFGRRKTEGVNPTAVELQVATA 432

  Fly   387 LFRHLQTSPSNMHGIDLVEQVNETKDDQTH----------SSGAYAFLSLINHSCAPNTVRIYEG 441
            |...||....|.|      |:.:|:..:.|          ::|.|...|..||.|.|:|...:.|
  Fly   433 LLGLLQVLQYNAH------QIYQTQVTEEHRFDGSKTVYLAAGLYGTGSYFNHECWPSTACHFVG 491

  Fly   442 TKAYMFVLRPIKAGNVLYDNYGAHFAICSKEQRLKRLSLQYRFDCKCEGCELNYPM 497
            .|..:...||.:|..::..|||..|...:.::|.:.|..:|.|.|.|..|:.|:|:
  Fly   492 KKLVLTATRPHRANELVAVNYGPIFIKNNLKERQRSLRGRYSFSCSCMACQENWPL 547

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Smyd4-4	NP_610730.1	TPR_11	67..138	CDD:290150	16/86 (19%)
		zf-MYND	230..270	CDD:280009	13/39 (33%)
		SET	363..463	CDD:279228	29/117 (25%)
Smyd4-2	NP_648574.1	TPR_11	142..205	CDD:290150	13/62 (21%)
		zf-MYND	299..338	CDD:280009	13/39 (33%)
		SET	<474..513	CDD:279228	12/38 (32%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E2759_KOG2084
Homologene	0	0.000	Not matched by this tool.
Inparanoid	1	1.050	136	1.000	Inparanoid score	I4533
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	1	1.010	-	-		D1278034at2759
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	1	1.000	-	-		otm3360
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	1	1.030	-	avgDist	Average_Evolutionary_Distance	R5130
SonicParanoid	0	0.000	Not matched by this tool.
	6	5.900