Protein Alignment Smyd4-4 and Smyd4-1

DIOPT Version :10

• Sequence 1: NP_610730.1
• Gene: Smyd4-4 / 36299
• FlyBaseID: FBgn0027495
• Length: 573
• Species: Drosophila melanogaster
• Sequence 2: NP_610500.2
• Gene: Smyd4-1 / 35985
• FlyBaseID: FBgn0033427
• Length: 751
• Species: Drosophila melanogaster
• Alignment Length: 600
• Identity: 145/600 - (24%)
• Similarity: 236/600 - (39%)
• Gaps: 132/600 - (22%)

  Fly    30 LKENHRKVDFVMRALIDFKY-IEKIF--LNVTLRED--------KCNKRSVEFRMLGNEQF---- 79
            |.||::......::|..... |.:||  |.:.|.:|        .|.:||...|..||..|
  Fly    17 LNENYKDEFETFKSLASMPADILQIFQKLALDLLQDLEQPVDRKGCAERSKNLREEGNLMFKESA 81

  Fly    80 --SLKNRNYFQALELYNKSICYAEPNSEHLSIGYANRSAVLFEWKRYRQCLDNIKLARQANYPAR 142
              |.|: :..:|..||::::..||...|.||:.:|||...|.|:..||:..|:...|.:..||.|
  Fly    82 SGSSKD-SVLKACRLYSEAVFEAENAVEELSLAFANRGIALQEYGYYREAYDDCSNALECGYPER 145

  Fly   143 LSHKLDKRERDCQ------QLLDQQPPDVVPYEFKLSFEPHAQVPFIADCLEL-------RETAA 194
            |.||:..|:..|.      ..|::....:...:.|.|||  .|:..:...|||       :||..
  Fly   146 LRHKVIMRQAFCAWKLKKIASLEEHLDYLGQLQLKESFE--QQLEDLKQKLELLKNQPREQETQG 208

  Fly   195 E----------------GRFVVTNRDLAVGDLVSVEEPFCSTLLTPMRYIRCATCKRENYLTLIP 243
            :                ||::|....::.|:::..|...|...|..:  :.|..|........||
  Fly   209 KVVDKSLGEILTDPGPRGRYMVAKEAISKGNVIFSERASCFVPLEQL--LICQQCAATLMSAPIP 271

  Fly   244 CDSCCS-TMFCSEECKSIAMQTYHRYECPII--DFLNRMFNKIHCIALRTTLVAL-NIFPSIEEL 304
            |.:|.. .::||.:|:. |....|::||...  |.| |:....| :|||..|..: .|.|.::|:
  Fly   272 CPNCHQRVVYCSRKCRE-AHSAIHKFECAAYRKDIL-RLLGISH-LALRLLLTYIPYIRPHLQEM 333

  Fly   305 ID---FCEQEQNQDKCAFDLNYNELTPEEHYRAIHGLVTNQHLRSVSDLFQR-------SVVCA- 358
            ..   ..|:..|..:          .|||...|...|   :.||.||.|.|.       .::||
  Fly   334 TSAKGMWEEIMNLSR----------KPEESENAPEYL---RSLRMVSQLDQAIDEELNYHILCAN 385

  Fly   359 VLKHFIIEYTPVKEYLGG-----EEGVNFFTDLLFRHLQTSPSNMH------GI----------- 401
            :|:.::.|:|...:....     |:.....:.|:.|......:|.|      |:
  Fly   386 LLQLYLKEHTDFYDQFHSLPASIEDWQLIISALILRFAGQLLANGHVGDALLGVGMEPKEFVMLQ 450

  Fly   402 -DLVEQVNETKDDQ----THSSGAYA----FLSLINHSCAPNTVRIYEGTKAYMFVLRPIKAGNV 457
             :|.::....|..|    :||....|    :|||.||:|.|:....::|.....:..:.|..|..
  Fly   451 PELWQKPRHLKRGQLHNLSHSDPITAINLPYLSLCNHACEPSIRTKFDGCSVVNYAAKDILEGEE 515

  Fly   458 LYDNYGAHFAICSKEQRLKRLSLQYRFDCKCEGCELNYPMFGMMPHKATVPSVTDDTELALSSYN 522
            :::.|...:....|.||...|...|:|:|.|..|                 :.||..:..||.:.
  Fly   516 IFNCYTMDYRNSLKLQRSHPLKAIYKFECTCAKC-----------------TRTDPDQNYLSFHR 563

  Fly   523 YDFAVSNYRKYCDFL 537
            |.....|.|:  :||
  Fly   564 YRCEKPNCRQ--EFL 576

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Smyd4-4	NP_610730.1	SET_SMYD4	180..491	CDD:380934	85/379 (22%)
		zf-MYND	230..270	CDD:460312	11/40 (28%)
Smyd4-1	NP_610500.2	SET	217..>252	CDD:394802	6/34 (18%)
		zf-MYND	258..298	CDD:460312	11/40 (28%)
		SET	<359..549	CDD:394802	43/192 (22%)