Protein Alignment Smyd4-4 and Smyd5

DIOPT Version :10

• Sequence 1: NP_610730.1
• Gene: Smyd4-4 / 36299
• FlyBaseID: FBgn0027495
• Length: 573
• Species: Drosophila melanogaster
• Sequence 2: NP_001101340.1
• Gene: Smyd5 / 312503
• RGDID: 1309153
• Length: 417
• Species: Rattus norvegicus
• Alignment Length: 410
• Identity: 90/410 - (21%)
• Similarity: 143/410 - (34%)
• Gaps: 129/410 - (31%)

  Fly   192 TAAEGRFVVTNRDLAVGDLVSVEEPFCSTLL---TPMRYIRCATCKR------ENYLTL------ 241
            ::|:|:.:...:.:..|:.:.:|.|..::..   ...||..|..|.|      ||...|
  Rat    29 SSAKGKGLFATQLIRKGETIFIERPLVASQFLWNALYRYRACDHCLRALEKAEENAQRLTGKPGQ 93

  Fly   242 -IP----C-------DSC--CSTMFCSEECKSIAMQTYHRYECP---------IIDFLNRMFNKI 283
             :|    |       .:|  |...:||.||:..|.:.||:..||         .::.|...:..:
  Rat    94 VLPHPELCSVRKDLHQNCPRCQVTYCSAECRLAAAEQYHQILCPGPSQDDPRHPLNKLQEAWRSV 158

  Fly   284 H------CIALRTTLVALNIFPSIEELID----------FCEQEQNQ----------DKCAFDLN 322
            |      .|.|...:||     ::::..|          ||.:..|:          ||....|.
  Rat   159 HYPPETASIMLMARMVA-----TVKQAKDKDHWVRLFSHFCSKTANEEEEIVHKLLGDKFKGQLE 218

  Fly   323 ----------YNE-----LTPEEHYRAIHGLV-TNQHLRSVSDLFQRSVVCAVLKHFIIEYTPVK 371
                      |.|     .|| :.:|::..|| ||......|.|.|....|..|     |..|.:
  Rat   219 LLRRLFTEALYEETLSQWFTP-DGFRSLFALVGTNGQGIGTSSLSQWVHACDAL-----ELKPQE 277

  Fly   372 EYLGGEEGVNFFTDLLFRHLQTSPSNMHGIDLVEQVNETKDDQTHSSGAYAFLSLINHSCAPNTV 436
                 .|.::.|.|.|::.::.:..        |.:|      ...||.:...|..||||.||..
  Rat   278 -----REQLDTFIDQLYKDIEAATG--------EFLN------CEGSGLFVLQSCCNHSCVPNAE 323

  Fly   437 RIYEGTKAYMFV--LRPIKAGNVLYDNYGAHFAICSKEQ----RLKRLSLQYRFDCKCEGCELNY 495
            ..:......:.|  |..|:.|..:..:|   ...|.:|:    |.|.|...|.|.|.|..|..
  Rat   324 TSFPENNFLLHVTALEDIEPGEEICISY---LDCCQRERSRHSRHKILRENYLFVCSCPKCLA-- 383

  Fly   496 PMFGMMPHKATVPSVTDDTE 515
                    :|..|:||.:.|
  Rat   384 --------EADDPNVTSEEE 395

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Smyd4-4	NP_610730.1	SET_SMYD4	180..491	CDD:380934	84/384 (22%)
		zf-MYND	230..270	CDD:460312	17/65 (26%)
Smyd5	NP_001101340.1	SET_SMYD5	22..384	CDD:380919	85/397 (21%)
		zf-MYND	101..136	CDD:480929	10/34 (29%)