Protein Alignment Smyd4-4 and Smyd2

DIOPT Version :10

• Sequence 1: NP_610730.1
• Gene: Smyd4-4 / 36299
• FlyBaseID: FBgn0027495
• Length: 573
• Species: Drosophila melanogaster
• Sequence 2: NP_996733.1
• Gene: Smyd2 / 289372
• RGDID: 727785
• Length: 433
• Species: Rattus norvegicus
• Alignment Length: 312
• Identity: 72/312 - (23%)
• Similarity: 118/312 - (37%)
• Gaps: 70/312 - (22%)

  Fly   192 TAAEGRFVVTNRDLAVGDLVSVEEPFCSTLLTPMRYIRCATC--KRENYLTLIPCDSCCSTMFCS 254
            :|.:||.:...|...||||:.....:...|....|...|..|  ::|.   |..|..|....:|.
  Rat    14 SAGKGRGLRALRPFHVGDLLFSCPAYACVLTVGERGHHCECCFARKEG---LSKCGRCKQAFYCD 75

  Fly   255 EECKSIAMQTYHRYECPIIDFLNRMFNKIHCIALRTTLVALNIFPSIEELIDFCEQEQNQDKCAF 319
            .||:. .....|:.||..:......:|....:.|...::|              :|:.:.::
  Rat    76 VECQK-EDWPLHKLECSSMVVFGENWNPSETVRLTARILA--------------KQKMHPER--- 122

  Fly   320 DLNYNELTPEEHYRAIHGLVTNQHLRSV----SDLFQRSVVCAVLKHFIIEYTPVKEYLGGEEGV 380
                   ||.|...|:...  ..||..:    .||.|..:  |.|..|   |:
  Rat   123 -------TPSEKLLAVREF--ESHLDKLDNEKKDLIQSDI--AALHQF---YS------------ 161

  Fly   381 NFFTDLLFRHLQTSPSNMHGIDLVEQVN----ETKDDQTHSSGAYAF--LSLINHSCAPNTVRIY 439
                    :||: .|.:...:.|..|||    ..:|::....|:..|  ::|:||||.||.:..|
  Rat   162 --------KHLE-FPDHSSLVVLFAQVNCNGFTIEDEELSHLGSAIFPDVALMNHSCCPNVIVTY 217

  Fly   440 EGTKAYMFVLRPIKAGNVLYDNYGAHFAICSKEQRLKRLSLQYRFDCKCEGC 491
            :||.|.:..::.|..|:.::.:|  ...:...|.|..||...|.|.|:|..|
  Rat   218 KGTLAEVRAVQEIHPGDEVFTSY--IDLLYPTEDRNDRLRDSYFFTCECREC 267

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Smyd4-4	NP_610730.1	SET_SMYD4	180..491	CDD:380934	71/310 (23%)
		zf-MYND	230..270	CDD:460312	10/41 (24%)
Smyd2	NP_996733.1	SET_SMYD2	7..269	CDD:380979	72/312 (23%)
		zf-MYND	52..90	CDD:460312	10/41 (24%)
		TPR_10	388..422	CDD:463861