Protein Alignment Smyd4-4 and set-14

DIOPT Version :10

• Sequence 1: NP_610730.1
• Gene: Smyd4-4 / 36299
• FlyBaseID: FBgn0027495
• Length: 573
• Species: Drosophila melanogaster
• Sequence 2: NP_496323.1
• Gene: set-14 / 174662
• WormBaseID: WBGene00011068
• Length: 429
• Species: Caenorhabditis elegans
• Alignment Length: 381
• Identity: 80/381 - (20%)
• Similarity: 130/381 - (34%)
• Gaps: 117/381 - (30%)

  Fly   215 EPFCSTLLTPMRYI-RCATCKRENYLTLIPCDSCCSTMFCSEECKSIAMQTYHRYECPIIDFLNR 278
            |.:|:..||.|..: :|:.|:|..|              ||:||:. |....|:.||..|...|.
 Worm    23 ESYCNQCLTSMAELKKCSACRRLAY--------------CSQECQR-ADWKLHKVECKAIKTHNE 72

  Fly   279 MFNKIHCIALRTTLVALNIFPSIEELIDFCEQEQNQDKCAFDLNYNELTPEEHYRAIHGLVTN-- 341
            :.|.    ::|..:                       :.|..|:.||....|.| .|.|:..|
 Worm    73 VAND----SIRLVM-----------------------RIAGKLSRNEDGEIEAY-YIPGVARNFQ 109

  Fly   342 --QHLRSVSDLFQRSVVCAVLKHFIIEYTPVKEYLGGEEGVNFFTDLLFRHLQ-------TSPSN 397
              :|..|..|..:.|.|....: |.|...|.::.:          .|:|:.:.       .|..|
 Worm   110 NLEHHPSSYDADEESFVKEYFQ-FAIAPHPDRDLI----------KLIFQKVSINSFVVGNSTGN 163

  Fly   398 MHGIDLVEQVNETKDDQTHSSGAYAFLSLINHSCAPNTVRIYEGTKAYMFVLRPIKAGNVLYDNY 462
            ..|:.|..:                 ||..||||.|.|...|....|   :|.|:.:........
 Worm   164 PIGVGLCIK-----------------LSAANHSCKPLTRVCYRNRTA---MLVPVSSELPSTLEG 208

  Fly   463 GAHFAI---CSKEQRLKRLSLQYRFDCKCEGCELNYPMFGMMPHKATVPSVTDDTELALSSYNYD 524
            ..|..|   ..::.|...|..:|:|.|:|:||                  :.:|....:.::...
 Worm   209 ACHSYIDELMPRDMRRDTLKKKYKFLCQCDGC------------------LDEDRNARMEAWTCG 255

  Fly   525 FAVSNYRK-----YCDFL--TQYGDDYPCEQISSAEEC-LKMALHIMADAVPLKAK 572
            ..|..:.:     .|:..  |...|.:  |...:|||. :.....:..||:||:.|
 Worm   256 ICVKGWMRNKENGQCELCGWTMSKDHF--ELCRTAEEAGIAARSRLANDAIPLETK 309

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Smyd4-4	NP_610730.1	SET_SMYD4	180..491	CDD:380934	64/290 (22%)
		zf-MYND	230..270	CDD:460312	10/39 (26%)
set-14	NP_496323.1	zf-MYND	26..64	CDD:460312	14/52 (27%)
		SET	75..241	CDD:394802	47/242 (19%)