DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment SkpB and SKP1

DIOPT Version :9

Sequence 1:	NP_610729.1	Gene:	SkpB / 36298	FlyBaseID:	FBgn0026176	Length:	161	Species:	Drosophila melanogaster
Sequence 2:	NP_010615.3	Gene:	SKP1 / 851928	SGDID:	S000002736	Length:	194	Species:	Saccharomyces cerevisiae

Alignment Length:	188	Identity:	76/188 - (40%)
Similarity:	110/188 - (58%)	Gaps:	33/188 - (17%)

- Green bases have known domain annotations that are detailed below.

  Fly     6 LESADKEIFDTDQEIAKCSETIRIAIEDL----------------------------GDESDNS- 41
            |.|.:.|.|..|::||:.|..::..:.|:                            ||:.|..
Yeast     8 LVSGEGERFTVDKKIAERSLLLKNYLNDMHDSNLQNNSDSESDSDSETNHKSKDNNNGDDDDEDD 72

  Fly    42 ---VLPLPNVNSLILKKVLHWATYHKDDPVVTEEVENKEKRTDDISSWDADFLKVDQGTLFELIL 103
               |:|:|||.|.:|:||:.||.:|:|.....|: ::..:::..:.|||.:||||||..|:|:||
Yeast    73 DEIVMPVPNVRSSVLQKVIEWAEHHRDSNFPDED-DDDSRKSAPVDSWDREFLKVDQEMLYEIIL 136

  Fly   104 AANYLNIQGLLDVTCKTVANMIKGKSPQAIRDTFAIQNDFLPQEEEQVRKENEWCEDK 161
            |||||||:.|||..||.||.||:|:||:.||.||.|.|||.|:||..:|:||||.||:
Yeast   137 AANYLNIKPLLDAGCKVVAEMIRGRSPEEIRRTFNIVNDFTPEEEAAIRRENEWAEDR 194

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
SkpB	NP_610729.1	SKP1	1..161	CDD:227528	75/186 (40%)
		Skp1	1..110	CDD:214704	44/135 (33%)
		Skp1	84..158	CDD:279768	47/73 (64%)
SKP1	NP_010615.3	SKP1	3..194	CDD:227528	75/186 (40%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C157344323
Domainoid	1	1.000	67	1.000	Domainoid score	I2347
eggNOG	1	0.900	-	-		E1_COG5201
Hieranoid	1	1.000	-	-
Homologene	0	0.000	Not matched by this tool.
Inparanoid	1	1.050	154	1.000	Inparanoid score	I1094
Isobase	1	0.950	-	0	Normalized mean entropy	S272
OMA	1	1.010	-	-		QHG54148
OrthoFinder	1	1.000	-	-		FOG0000367
OrthoInspector	1	1.000	-	-		otm46619
orthoMCL	1	0.900	-	-		OOG6_100934
Panther	1	1.100	-	-	O	PTHR11165
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	1	1.000	-	-		X346
TreeFam	1	0.960	-	-
	14	13.710