Protein Alignment SkpB and SKP1

DIOPT Version :9

• Sequence 1: NP_610729.1
• Gene: SkpB / 36298
• FlyBaseID: FBgn0026176
• Length: 161
• Species: Drosophila melanogaster
• Sequence 2: NP_733779.1
• Gene: SKP1 / 6500
• HGNCID: 10899
• Length: 163
• Species: Homo sapiens
• Alignment Length: 163
• Identity: 113/163 - (69%)
• Similarity: 134/163 - (82%)
• Gaps: 2/163 - (1%)

  Fly     1 MPIIRLESADKEIFDTDQEIAKCSETIRIAIEDLG--DESDNSVLPLPNVNSLILKKVLHWATYH 63
            ||.|:|:|:|.|||:.|.||||.|.||:..:||||  ||.|:..:||||||:.|||||:.|.|:|
Human     1 MPSIKLQSSDGEIFEVDVEIAKQSVTIKTMLEDLGMDDEGDDDPVPLPNVNAAILKKVIQWCTHH 65

  Fly    64 KDDPVVTEEVENKEKRTDDISSWDADFLKVDQGTLFELILAANYLNIQGLLDVTCKTVANMIKGK 128
            ||||...|:.||||||||||..||.:|||||||||||||||||||:|:|||||||||||||||||
Human    66 KDDPPPPEDDENKEKRTDDIPVWDQEFLKVDQGTLFELILAANYLDIKGLLDVTCKTVANMIKGK 130

  Fly   129 SPQAIRDTFAIQNDFLPQEEEQVRKENEWCEDK 161
            :|:.||.||.|:|||..:||.||||||:|||:|
Human   131 TPEEIRKTFNIKNDFTEEEEAQVRKENQWCEEK 163

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
SkpB	NP_610729.1	SKP1	1..161	CDD:227528	112/161 (70%)
		Skp1	1..110	CDD:214704	74/110 (67%)
		Skp1	84..158	CDD:279768	56/73 (77%)
SKP1	NP_733779.1	BTB_POZ_SKP1	4..127	CDD:349631	85/122 (70%)
		Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite	63..83		13/19 (68%)
		Interaction with the F-box domain of F-box proteins. /evidence=ECO:0000250	104..163		45/58 (78%)
		Skp1	113..160	CDD:396171	34/46 (74%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C165149266
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_COG5201
Hieranoid	1	1.000	-	-
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	1	1.010	-	-		QHG54148
OrthoDB	1	1.010	-	-		D1412723at2759
OrthoFinder	1	1.000	-	-		FOG0000367
OrthoInspector	1	1.000	-	-		otm41331
orthoMCL	1	0.900	-	-		OOG6_100934
Panther	1	1.100	-	-	O	PTHR11165
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	1	1.000	-	-		X346
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	1	0.960	-	-
User_Submission	0	0.000	Not matched by this tool.
	12	11.720