DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment SkpB and skr-14

DIOPT Version :9

Sequence 1:	NP_610729.1	Gene:	SkpB / 36298	FlyBaseID:	FBgn0026176	Length:	161	Species:	Drosophila melanogaster
Sequence 2:	NP_504220.4	Gene:	skr-14 / 178839	WormBaseID:	WBGene00004820	Length:	168	Species:	Caenorhabditis elegans

Alignment Length:	142	Identity:	54/142 - (38%)
Similarity:	77/142 - (54%)	Gaps:	13/142 - (9%)

- Green bases have known domain annotations that are detailed below.

  Fly    12 EIFDTDQEIAKCSE-------TIRIAIEDLGDESDN----SVLPLPNVNSLILKKVLHWATYHKD 65
            :|...|..:.|.||       |:...||:||...:|    ..:|:.|||...::||..|...|..
Worm    16 KIISNDGVVTKMSEKAVQQSKTLSNLIENLGYTIENIETRDPIPVTNVNGKTMEKVAEWCEKHNA 80

  Fly    66 DPVVTEEVENKEKRTDDISSWDADFLKVDQGTLFELILAANYLNIQGLLDVTCKTVANMIKGKSP 130
            | .:.|:..|..| |..|..||..|||::...||:||||:|:|:|:||:...||||:||.|||:.
Worm    81 D-AIPEDNMNVLK-TLTIPEWDQKFLKIEDEALFDLILASNFLDIKGLMYYGCKTVSNMAKGKTT 143

  Fly   131 QAIRDTFAIQND 142
            ..:|:.|.|..|
Worm   144 AELREIFGINTD 155

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
SkpB	NP_610729.1	SKP1	1..161	CDD:227528	54/142 (38%)
		Skp1	1..110	CDD:214704	38/108 (35%)
		Skp1	84..158	CDD:279768	29/59 (49%)
skr-14	NP_504220.4	Skp1	12..123	CDD:214704	38/108 (35%)
skr-14	NP_504220.4	Skp1	97..161	CDD:279768	29/59 (49%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C160160682
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_COG5201
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	1	0.950	-	0	Normalized mean entropy	S272
OMA	1	1.010	-	-		QHG54148
OrthoDB	1	1.010	-	-		D1412723at2759
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	1	1.100	-	-	O	PTHR11165
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	1	1.000	-	-
TreeFam	0	0.000	Not matched by this tool.
	8	7.810