Protein Alignment CG8888 and RDH16

DIOPT Version :9

• Sequence 1: NP_610724.1
• Gene: CG8888 / 36293
• FlyBaseID: FBgn0033679
• Length: 388
• Species: Drosophila melanogaster
• Sequence 2: NP_003699.3
• Gene: RDH16 / 8608
• HGNCID: 29674
• Length: 317
• Species: Homo sapiens
• Alignment Length: 305
• Identity: 94/305 - (30%)
• Similarity: 148/305 - (48%)
• Gaps: 45/305 - (14%)

  Fly    73 VWFALAT-VGAVLFYHF-----VKVSASGKGVLITGCEAPLAWYLAKKLDDLGFTVYAGFNTPIE 131
            :|..||. ||.....|:     |......|.|.||||::.....||::||..|..|.|...|
Human     1 MWLYLAVFVGLYYLLHWYRERQVLSHLRDKYVFITGCDSGFGKLLARQLDARGLRVLAACLT--- 62

  Fly   132 ESDEAKILKEVTSGRMKLLHLDVTSEKTILEAARYVSQHLPHGAEGLWSVVHCAHWIALG-ELEW 195
             ...|:.|:..||.|::.:.||||..:::..||::|.:.:..  :|||.:|:.|     | .|..
Human    63 -EKGAEQLRGQTSDRLETVTLDVTKTESVAAAAQWVKECVRD--KGLWGLVNNA-----GISLPT 119

  Fly   196 IPFAVLRKS-----LDLNLLGSARLTQIFLPLVRRAHGRVVFLTSGLNRVPSPVRGIQCATQAAV 255
            .|..:|.|.     ||:||||...:|...|||||||.||||.::|.:.|| |...|..|.::..|
Human   120 APNELLTKQDFVTILDVNLLGVIDVTLSLLPLVRRARGRVVNVSSVMGRV-SLFGGGYCISKYGV 183

  Fly   256 DCFAACLRQEMRTRGVDVSVVAAGEFAPGNGWLNETELRDQAK------QMWNQLSSEQKKTYGE 314
            :.|:..||:|:...||.|:::..|.|        :|.:..:.:      ::|::.|.|.|:.|||
Human   184 EAFSDSLRRELSYFGVKVAMIEPGYF--------KTAVTSKERFLKSFLEIWDRSSPEVKEAYGE 240

  Fly   315 ----DYYEAAMTSVEKYSRQAADIQPTLRVLIDAVTRTFPMARYT 355
                ||.::|....:|.::   |:......:..|:....|..||:
Human   241 KFVADYKKSAEQMEQKCTQ---DLSLVTNCMEHALIACHPRTRYS 282

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
CG8888	NP_610724.1	NADB_Rossmann	96..380	CDD:304358	87/276 (32%)
		adh_short	96..293	CDD:278532	71/202 (35%)
RDH16	NP_003699.3	NADB_Rossmann	30..305	CDD:304358	87/276 (32%)
		adh_short	30..218	CDD:278532	71/207 (34%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	1	1.000	125	1.000	Domainoid score	I5479
eggNOG	1	0.900	-	-		E1_KOG1610
Hieranoid	1	1.000	-	-
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	1	0.950	-	1	Normalized mean entropy	S2603
OMA	1	1.010	-	-		QHG48608
OrthoDB	1	1.010	-	-		D370032at33208
OrthoFinder	1	1.000	-	-		FOG0000161
OrthoInspector	1	1.000	-	-		otm41558
orthoMCL	0	0.000	Not matched by this tool.
Panther	1	1.100	-	-	LDO	PTHR43313
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	1	1.000	-	-		X110
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
User_Submission	0	0.000	Not matched by this tool.
	11	10.880