Protein Alignment CG8888 and AYR1

DIOPT Version :10

• Sequence 1: NP_610724.1
• Gene: CG8888 / 36293
• FlyBaseID: FBgn0033679
• Length: 388
• Species: Drosophila melanogaster
• Sequence 2: NP_012142.3
• Gene: AYR1 / 854682
• SGDID: S000001386
• Length: 297
• Species: Saccharomyces cerevisiae
• Alignment Length: 233
• Identity: 51/233 - (21%)
• Similarity: 97/233 - (41%)
• Gaps: 31/233 - (13%)

  Fly    96 KGVLITGCEAPLAWYLAKKLDDLGFTVYAGFN--TPIEESDEAKILKEVTSGRMKLLHLDVTSEK 158
            |..::||....:.:.:.|:|...|:.|||...  .|:     |::..:..:..:|...||::..:
Yeast    10 KIAVVTGASGGIGYEVTKELARNGYLVYACARRLEPM-----AQLAIQFGNDSIKPYKLDISKPE 69

  Fly   159 TILEAARYVSQHLPHGAEGLW--SVVHCAHWIALGELEWIPFAVLRKSLDLNLLGSARLTQIFLP 221
            .|:..:.::..:||.|...|.  :......:.||...:    |.:.:...:|:.|...:.:....
Yeast    70 EIVTFSGFLRANLPDGKLDLLYNNAGQSCTFPALDATD----AAVEQCFKVNVFGHINMCRELSE 130

  Fly   222 LVRRAHGRVVFLTSGLNRVPSPVRGIQCATQAAVDCFAACLRQEMRTRGVDVSVVAAGEFA---- 282
            .:.:|.|.:||..|....|..|...|..|::||:..:|..|..||:...|.|.....|..|
Yeast   131 FLIKAKGTIVFTGSLAGVVSFPFGSIYSASKAAIHQYARGLHLEMKPFNVRVINAITGGVATDIA 195

  Fly   283 ---PGNGWLNETELRD--QAKQMWNQLSSEQKKTYGED 315
               |    |.||.:.:  :.::.:|     .:||..:|
Yeast   196 DKRP----LPETSIYNFPEGREAFN-----SRKTMAKD 224

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
CG8888	NP_610724.1	Rossmann-fold NAD(P)(+)-binding proteins	96..380	CDD:473865	51/233 (22%)
AYR1	NP_012142.3	17beta-HSD-like_SDR_c	10..256	CDD:187632	51/233 (22%)