DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment CG8888 and Sdr9c7

DIOPT Version :9

Sequence 1:	NP_610724.1	Gene:	CG8888 / 36293	FlyBaseID:	FBgn0033679	Length:	388	Species:	Drosophila melanogaster
Sequence 2:	NP_081577.1	Gene:	Sdr9c7 / 70061	MGIID:	1917311	Length:	313	Species:	Mus musculus

Alignment Length:	321	Identity:	92/321 - (28%)
Similarity:	164/321 - (51%)	Gaps:	35/321 - (10%)

- Green bases have known domain annotations that are detailed below.

  Fly    63 ISSISTFA-VFVWFALATVGAVLFYHFVKVSASGKGVLITGCEAPLAWYLAKKLDDLGFTVYAGF 126
            :::::.|| ::.||...        :.|| :.|.|.|.||||::.....|||:|.|.|..|.|..
Mouse     1 MAALTDFAFMYRWFKNC--------NLVK-NLSEKYVFITGCDSGFGNLLAKQLVDRGMKVLAAC 56

  Fly   127 NTPIEESDEAKILKEVTSGRMKLLHLDVTSEKTILEAARYVSQHLPHGAEGLWSVVHCAH-WIAL 190
            .|   |....|:|:: ||.:::...||||..:.:.|||::|...:  |.:|||::|:.|. .:..
Mouse    57 LT---EEGAQKLLQD-TSHQLQTFLLDVTKSENVKEAAQWVRDQV--GEQGLWALVNNAGVGLPS 115

  Fly   191 GELEWIPFAVLRKSLDLNLLGSARLTQIFLPLVRRAHGRVVFLTSGLNRVPSPVRGIQCATQAAV 255
            |..||:......|.:::||:|...:|...||::::|.||||.::|...|| :...|..|.::..|
Mouse   116 GPNEWLTIKDFVKVININLVGLIDVTLNMLPMIKKARGRVVNMSSSGGRV-AIFGGGYCVSKFGV 179

  Fly   256 DCFAACLRQEMRTRGVDVSVVAAGEFAPGNGWLNETELRDQAKQMWNQLSSEQKKTYGEDYYEAA 320
            :.|:..:|:|:...||.||::..|.:.  ...|.:..|..:.|::|::|..|.:.:|||:|::.
Mouse   180 EAFSDSIRRELHFFGVKVSIIEPGNYK--TSILGQEALESRMKKLWDRLPQETRDSYGEEYFQT- 241

  Fly   321 MTSVEKYSRQAADIQPTLRVLIDAVTRTF--------PMARYTPVTSSERLQIFLAEHLAP 373
                  |:::..::..:....|..||.:.        |..||.|....:.|.:.||:...|
Mouse   242 ------YTKKLVNLMRSAEPRISDVTNSMEHAIVSRSPRIRYNPGLDVKFLYLTLAKLPTP 296

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG8888	NP_610724.1	NADB_Rossmann	96..380	CDD:304358	85/287 (30%)
CG8888	NP_610724.1	adh_short	96..293	CDD:278532	64/197 (32%)
Sdr9c7	NP_081577.1	type2_17beta_HSD-like_SDR_c	26..302	CDD:187665	85/287 (30%)
Sdr9c7	NP_081577.1	adh_short	26..207	CDD:278532	63/189 (33%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	1	1.000	120	1.000	Domainoid score	I5728
eggNOG	1	0.900	-	-		E1_KOG1610
Hieranoid	1	1.000	-	-
Homologene	0	0.000	Not matched by this tool.
Inparanoid	1	1.050	163	1.000	Inparanoid score	I4195
Isobase	0	0.000	Not matched by this tool.
OMA	1	1.010	-	-		QHG48608
OrthoDB	1	1.010	-	-		D370032at33208
OrthoFinder	1	1.000	-	-		FOG0000161
OrthoInspector	1	1.000	-	-		otm43606
orthoMCL	0	0.000	Not matched by this tool.
Panther	1	1.100	-	-	O	PTHR43313
Phylome	1	0.910	-	-
RoundUp	1	1.030	-	avgDist	Average_Evolutionary_Distance	R1882
SonicParanoid	1	1.000	-	-		X110
SwiftOrtho	1	1.000	-	-
TreeFam	0	0.000	Not matched by this tool.
	13	13.010