Protein Alignment CG8888 and BDH1

DIOPT Version :9

• Sequence 1: NP_610724.1
• Gene: CG8888 / 36293
• FlyBaseID: FBgn0033679
• Length: 388
• Species: Drosophila melanogaster
• Sequence 2: XP_011511369.1
• Gene: BDH1 / 622
• HGNCID: 1027
• Length: 347
• Species: Homo sapiens
• Alignment Length: 286
• Identity: 95/286 - (33%)
• Similarity: 153/286 - (53%)
• Gaps: 1/286 - (0%)

  Fly    96 KGVLITGCEAPLAWYLAKKLDDLGFTVYAGFNTPIEESDEAKILKEVTSGRMKLLHLDVTSEKTI 160
            |.||:|||::...:.|||.|...||.|:||.....:..|..|.|..:.|.|::.:.|:|.|.:.:
Human    60 KAVLVTGCDSGFGFSLAKHLHSKGFLVFAGCLMKDKGHDGVKELDSLNSDRLRTVQLNVCSSEEV 124

  Fly   161 LEAARYVSQHLPHGAEGLWSVVHCAHWIALGELEWIPFAVLRKSLDLNLLGSARLTQIFLPLVRR 225
            .:....|...|....:|:|.:|:.|.....||:|:......::..::||.|:.|:|:.||||:||
Human   125 EKVVEIVRSSLKDPEKGMWGLVNNAGISTFGEVEFTSLETYKQVAEVNLWGTVRMTKSFLPLIRR 189

  Fly   226 AHGRVVFLTSGLNRVPSPVRGIQCATQAAVDCFAACLRQEMRTRGVDVSVVAAGEFAPGNGWLNE 290
            |.||||.::|.|.|:.:|.|...|.|:..|:.|:.|||.||...||.||||..|.|.......:.
Human   190 AKGRVVNISSMLGRMANPARSPYCITKFGVEAFSDCLRYEMYPLGVKVSVVEPGNFIAATSLYSP 254

  Fly   291 TELRDQAKQMWNQLSSEQKKTYGEDYYEAAMTSVEKY-SRQAADIQPTLRVLIDAVTRTFPMARY 354
            ..::..||:||.:|....:|.||:.|::..:..:|.| |..:.|..|.:..:..|:|.|.|..||
Human   255 ESIQAIAKKMWEELPEVVRKDYGKKYFDEKIAKMETYCSSGSTDTSPVIDAVTHALTATTPYTRY 319

  Fly   355 TPVTSSERLQIFLAEHLAPSLYESLY 380
            .|:.....|::.:..||..::.:.:|
Human   320 HPMDYYWWLRMQIMTHLPGAISDMIY 345

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
CG8888	NP_610724.1	NADB_Rossmann	96..380	CDD:304358	94/284 (33%)
		adh_short	96..293	CDD:278532	70/196 (36%)
BDH1	XP_011511369.1	type2_17beta_HSD-like_SDR_c	60..345	CDD:187665	94/284 (33%)
		adh_short	60..245	CDD:278532	69/184 (38%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	1	1.000	125	1.000	Domainoid score	I5479
eggNOG	1	0.900	-	-		E1_KOG1610
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	1	1.050	170	1.000	Inparanoid score	I4137
Isobase	0	0.000	Not matched by this tool.
OMA	1	1.010	-	-		QHG48608
OrthoDB	1	1.010	-	-		D1390068at2759
OrthoFinder	1	1.000	-	-		FOG0000161
OrthoInspector	1	1.000	-	-		otm41558
orthoMCL	1	0.900	-	-		OOG6_109704
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	1	1.000	-	-		X110
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	1	0.960	-	-
User_Submission	0	0.000	Not matched by this tool.
	11	10.740