Protein Alignment CG8888 and RDH8

DIOPT Version :9

• Sequence 1: NP_610724.1
• Gene: CG8888 / 36293
• FlyBaseID: FBgn0033679
• Length: 388
• Species: Drosophila melanogaster
• Sequence 2: NP_056540.3
• Gene: RDH8 / 50700
• HGNCID: 14423
• Length: 311
• Species: Homo sapiens
• Alignment Length: 302
• Identity: 65/302 - (21%)
• Similarity: 122/302 - (40%)
• Gaps: 69/302 - (22%)

  Fly    91 VSASGKGVLITGCEAPLAWYLAKKL--------------DDLGFTVYAGFNTPIEESDEAKILKE 141
            ::|:.:.|||:||.:.:...||.:|              .|||          .:|:.|| ...|
Human     1 MAAAPRTVLISGCSSGIGLELAVQLAHDPKKRYQVVATMRDLG----------KKETLEA-AAGE 54

  Fly   142 VTSGRMKLLHLDVTSEKTILEAARYVSQHLPHGAEGLWSVVHCAHWIALGELEWIPFAVLRKSLD 206
            .....:.:..|||.|::::.:....:...:.       .:|:.|....:|.||.:..|.::...|
Human    55 ALGQTLTVAQLDVCSDESVAQCLSCIQGEVD-------VLVNNAGMGLVGPLEGLSLAAMQNVFD 112

  Fly   207 LNLLGSARLTQIFLP-LVRRAHGRVVFLTSGLNRVPSPVRGIQ--------CATQAAVDCFAACL 262
            .|..|:.||.:..|| :.||..|.:|.::|        |.|:|        .|::.|::.|...|
Human   113 TNFFGAVRLVKAVLPGMKRRRQGHIVVISS--------VMGLQGVIFNDVYAASKFALEGFFESL 169

  Fly   263 RQEMRTRGVDVSVVAAG----EFAPGNGWLNETELRDQAKQMWNQLSSEQKKTYGEDYYEAAMTS 323
            ..::....:.:|:|..|    ||        |.:|..|........:..:...|..|.|..|  |
Human   170 AIQLLQFNIFISLVEPGPVVTEF--------EGKLLAQVSMAEFPGTDPETLHYFRDLYLPA--S 224

  Fly   324 VEKYSRQAADIQPTLRVLIDAVTRTFP------MARYTPVTS 359
            .:.:.....:.|..::.:::.::.|.|      ..||:|:|:
Human   225 RKLFCSVGQNPQDVVQAIVNVISSTRPPLRRQTNIRYSPLTT 266

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
CG8888	NP_610724.1	NADB_Rossmann	96..380	CDD:304358	64/297 (22%)
		adh_short	96..293	CDD:278532	50/223 (22%)
RDH8	NP_056540.3	type1_17beta-HSD-like_SDR_c	6..262	CDD:187666	61/291 (21%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
User_Submission	0	0.000	Not matched by this tool.
	1	0.910