DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment CG8888 and dhrs9

DIOPT Version :9

Sequence 1:	NP_610724.1	Gene:	CG8888 / 36293	FlyBaseID:	FBgn0033679	Length:	388	Species:	Drosophila melanogaster
Sequence 2:	NP_001001191.1	Gene:	dhrs9 / 407852	XenbaseID:	XB-GENE-973205	Length:	322	Species:	Xenopus tropicalis

Alignment Length:	305	Identity:	83/305 - (27%)
Similarity:	155/305 - (50%)	Gaps:	31/305 - (10%)

- Green bases have known domain annotations that are detailed below.

  Fly    80 VGAVLFYHFVKV-------SASGKGVLITGCEAPLAWYLAKKLDDLGFTVYAGFNTPIEESDEAK 137
            :|..:.|.:.:|       :.:.|.:|||||:.....:.||..|..||.:.|   |.:.|:. |.
Frog     7 IGVAILYIWWRVRDGLKINNITEKYILITGCDTGFGNHAAKTFDKQGFRILA---TCLTEAG-AT 67

  Fly   138 ILKEVTSGRMKLLHLDVTSEKTILEAARYVSQHLPHGAEGLWSVVHCAHWI-ALGELEWIPFAVL 201
            .|:|.||.|:|...||||..:.::..|.:|...:  |:.|||.:::.|..: .|...:|:....:
Frog    68 GLREATSQRLKTTLLDVTIAENVVSMAEWVKGEV--GSRGLWGLINNAGVMGTLAPFDWLTIEDI 130

  Fly   202 RKSLDLNLLGSARLTQIFLPLVRRAHGRVVFLTSGLNRVPSPVRGIQCATQAAVDCFAACLRQEM 266
            :|.:::||:|...:|.:.||.:::|.||::.::|...||.:. .|...:::..|:.|...||::|
Frog   131 KKPMEINLIGLIHVTLVLLPFIKKAKGRIINVSSIGGRVAAS-GGAYFSSKFGVEGFNDSLRRDM 194

  Fly   267 RTRGVDVSVVAAGEFAPGNGWLNETELRD------QAKQMWNQLSSEQKKTYGEDYYEAAMTSVE 325
            :..||.||.:..|.|        :|.|.|      |...:|.:|.:|.:|.||::|.:...:..:
Frog   195 KAFGVQVSCIEPGLF--------KTPLSDPKKVLQQRTDIWKRLPTEIQKEYGDNYIQIDASKKQ 251

  Fly   326 KYSRQA--ADIQPTLRVLIDAVTRTFPMARYTPVTSSERLQIFLA 368
            |.:::.  .|:...::.:..|:|...|..||:..:.:..|.|.|:
Frog   252 KLNQRILNTDLSLVVQCMEHALTSRHPRTRYSAGSDAAFLWIPLS 296

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG8888	NP_610724.1	NADB_Rossmann	96..380	CDD:304358	80/282 (28%)
CG8888	NP_610724.1	adh_short	96..293	CDD:278532	60/197 (30%)
dhrs9	NP_001001191.1	type2_17beta_HSD-like_SDR_c	30..307	CDD:187665	80/282 (28%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	1	1.010	-	-		D370032at33208
OrthoFinder	1	1.000	-	-		FOG0000161
OrthoInspector	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	0	0.000	Not matched by this tool.
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	1	1.000	-	-		X110
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	3	3.010