Protein Alignment CG8888 and Rdh7

DIOPT Version :10

• Sequence 1: NP_610724.1
• Gene: CG8888 / 36293
• FlyBaseID: FBgn0033679
• Length: 388
• Species: Drosophila melanogaster
• Sequence 2: NP_598227.3
• Gene: Rdh7 / 360420
• RGDID: 631370
• Length: 317
• Species: Rattus norvegicus
• Alignment Length: 291
• Identity: 95/291 - (32%)
• Similarity: 149/291 - (51%)
• Gaps: 17/291 - (5%)

  Fly    73 VW-FALATVG----AVLFYHFVKVS-ASGKGVLITGCEAPLAWYLAKKLDDLGFTVYAGFNTPIE 131
            :| :.||.||    ..||.....|| ...|.|.||||::.....||::||..|..|.|...|
  Rat     1 MWLYLLALVGLWNLLRLFRERKVVSHLQDKYVFITGCDSGFGNLLARQLDRRGMRVLAACLT--- 62

  Fly   132 ESDEAKILKEVTSGRMKLLHLDVTSEKTILEAARYVSQHLPHGAEGLWSVVHCAH-WIALGELEW 195
             ...|:.|:..||.|::.:.||||..::|:.|.::|.:.:  |..|||.:|:.|. .:.:|..||
  Rat    63 -EKGAEQLRSKTSDRLETVILDVTKTESIVAATQWVKERV--GNRGLWGLVNNAGISVPMGPNEW 124

  Fly   196 IPFAVLRKSLDLNLLGSARLTQIFLPLVRRAHGRVVFLTSGLNRVPSPVRGIQCATQAAVDCFAA 260
            :........||:||||...:|...|||||:|.||||.:.|.:.|: |.:.|..|.::..|:.|:.
  Rat   125 MRKKDFASVLDVNLLGVIEVTLNMLPLVRKARGRVVNIASTMGRM-SLLGGGYCISKYGVEAFSD 188

  Fly   261 CLRQEMRTRGVDVSVVAAGEFAPGNGWLNETELRDQAKQMWNQLSSEQKKTYGEDYYEAAMTSVE 325
            .||:|:...||.|:::..|.|.  ....|...|.|..|::|:|.:.|.|:.|||.:.::.|.::|
  Rat   189 SLRRELTYFGVKVAIIEPGGFK--TNVTNMERLSDNLKKLWDQATEEVKEIYGEKFRDSYMKAME 251

  Fly   326 KYSRQ-AADIQPTLRVLIDAVTRTFPMARYT 355
            ..... :.|:......:..|:|...|..||:
  Rat   252 SLVNMCSGDLSLVTDCMEHALTSCHPRTRYS 282

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
CG8888	NP_610724.1	Rossmann-fold NAD(P)(+)-binding proteins	96..380	CDD:473865	86/262 (33%)
Rdh7	NP_598227.3	type2_17beta_HSD-like_SDR_c	30..306	CDD:187665	86/262 (33%)