Protein Alignment CG8888 and CG6012

DIOPT Version :10

• Sequence 1: NP_610724.1
• Gene: CG8888 / 36293
• FlyBaseID: FBgn0033679
• Length: 388
• Species: Drosophila melanogaster
• Sequence 2: NP_609817.1
• Gene: CG6012 / 35022
• FlyBaseID: FBgn0032615
• Length: 308
• Species: Drosophila melanogaster
• Alignment Length: 330
• Identity: 62/330 - (18%)
• Similarity: 113/330 - (34%)
• Gaps: 117/330 - (35%)

  Fly    45 LFCQAAAIVTSHLLHALDISSISTFAVFVWFALATVGAVLFYHFVKV------------------ 91
            :||..:|.:|...::||        :.:::..|.|.     |..:|:
  Fly     1 MFCALSAFLTFVGVYAL--------SSYLYEQLRTP-----YKLIKIRYFSGTRPTLKERFGDWA 52

  Fly    92 ----SASGKG--------------VLITGCEAPLAWYLAKKLDDLGFTVYAGFNTPIEESDEAK- 137
                ::.|.|              |||...|..|. .:||::.|.|    ||..|.|..:|..|
  Fly    53 AVTGASDGIGKEYAKELARQNINVVLIARTEEKLQ-AVAKEIADCG----AGVQTKIVIADFTKG 112

  Fly   138 ------ILKEVTSGRMKLL--HLDVTSEKTILEAARYVSQHLPHGAEGLWSVVHCAHWIALGELE 194
                  |.||..:..:.:|  ::.:.:.|::|:..:..:|::
  Fly   113 SQVYEHIEKETANIPISILVNNVGIATPKSLLKYNQEETQNI----------------------- 154

  Fly   195 WIPFAVLRKSLDLNLLGSARLTQIFLPLVR--RAHGRVVFLTSGLNRVPSPVRGIQCATQAAVDC 257
                      :|.|::..::|::||...::  :..|.:|.:.||....|.|......|::|....
  Fly   155 ----------IDTNVVAVSQLSRIFFQRMKASKLKGAIVNVGSGTELQPLPNGAYYAASKAYTRS 209

  Fly   258 FAACLRQEMRTRGVDVSVVAAGEFAPG--------------NGWLNETELRDQAKQMWNQLSSEQ 308
            ....|..|.:..|:.|.::     :|.              .|.|........||...|||..|.
  Fly   210 LTLALYHEAKPYGIHVQML-----SPNFVVTKINSYSRQIMKGGLLIPSASAYAKSAVNQLRDEV 269

  Fly   309 KKTYG 313
            .:|.|
  Fly   270 DETPG 274

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
CG8888	NP_610724.1	Rossmann-fold NAD(P)(+)-binding proteins	96..380	CDD:473865	51/257 (20%)
CG6012	NP_609817.1	17beta-HSD1_like_SDR_c	49..296	CDD:187614	52/269 (19%)