DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment CG8888 and Sdr9c7

DIOPT Version :9

Sequence 1:	NP_610724.1	Gene:	CG8888 / 36293	FlyBaseID:	FBgn0033679	Length:	388	Species:	Drosophila melanogaster
Sequence 2:	XP_006241577.1	Gene:	Sdr9c7 / 259235	RGDID:	628716	Length:	313	Species:	Rattus norvegicus

Alignment Length:	321	Identity:	90/321 - (28%)
Similarity:	166/321 - (51%)	Gaps:	35/321 - (10%)

- Green bases have known domain annotations that are detailed below.

  Fly    63 ISSISTFA-VFVWFALATVGAVLFYHFVKVSASGKGVLITGCEAPLAWYLAKKLDDLGFTVYAGF 126
            :::::.|| ::.||...        :.|| :.|.|.|.||||::.....||::|.|.|..|.|..
  Rat     1 MAALTDFAFMYRWFKNC--------NLVK-NLSEKYVFITGCDSGFGNLLARQLVDRGMKVLAAC 56

  Fly   127 NTPIEESDEAKILKEVTSGRMKLLHLDVTSEKTILEAARYVSQHLPHGAEGLWSVVHCAH-WIAL 190
            .|   |....|:|:: ||.::::..||||..:::..||::|...:  |.:|||::|:.|. .:..
  Rat    57 LT---EEGAQKLLQD-TSYQLQIFLLDVTKSESVKAAAQWVRDQV--GEQGLWALVNNAGVGLPS 115

  Fly   191 GELEWIPFAVLRKSLDLNLLGSARLTQIFLPLVRRAHGRVVFLTSGLNRVPSPVRGIQCATQAAV 255
            |..||:......|.:::||:|...:|...||::::|.||||.::|...|| :.:.|..|.::..|
  Rat   116 GPNEWLTKEDFVKVININLVGLIDVTLNMLPMLKKARGRVVNMSSSGGRV-AVIGGGYCVSKFGV 179

  Fly   256 DCFAACLRQEMRTRGVDVSVVAAGEFAPGNGWLNETELRDQAKQMWNQLSSEQKKTYGEDYYEAA 320
            :.|:..:|:|:...||.||::..|.:.  ...|.:..|:.:.:::|::|..|.:.:|||:|::.
  Rat   180 EAFSDSIRRELHFFGVKVSIIEPGNYK--TSILGQEALQSRMRKLWDRLPQETRDSYGEEYFQT- 241

  Fly   321 MTSVEKYSRQAADIQPTLRVLIDAVTRTF--------PMARYTPVTSSERLQIFLAEHLAP 373
                  |:.:..::..|....|..||.:.        |..||.|....:.|.|.|::...|
  Rat   242 ------YTDKLVNLMRTAEPRISDVTNSMEHAIVSRSPRIRYNPGLDVKLLYIPLSKLPTP 296

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG8888	NP_610724.1	NADB_Rossmann	96..380	CDD:304358	83/287 (29%)
CG8888	NP_610724.1	adh_short	96..293	CDD:278532	62/197 (31%)
Sdr9c7	XP_006241577.1	type2_17beta_HSD-like_SDR_c	26..302	CDD:187665	83/287 (29%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	1	1.000	120	1.000	Domainoid score	I5601
eggNOG	1	0.900	-	-		E1_KOG1610
Hieranoid	1	1.000	-	-
Homologene	0	0.000	Not matched by this tool.
Inparanoid	1	1.050	164	1.000	Inparanoid score	I4098
OMA	1	1.010	-	-		QHG48608
OrthoDB	1	1.010	-	-		D370032at33208
OrthoFinder	1	1.000	-	-		FOG0000161
OrthoInspector	1	1.000	-	-		otm45679
orthoMCL	0	0.000	Not matched by this tool.
Panther	1	1.100	-	-	O	PTHR43313
Phylome	1	0.910	-	-
SonicParanoid	1	1.000	-	-		X110
SwiftOrtho	1	1.000	-	-
TreeFam	0	0.000	Not matched by this tool.
	12	11.980