DRSC/TRiP Functional Genomics Resources

powered by:
logo

back to: DIOPT - Ortholog Prediction Tool / DIOPT for Diseases and Traits


Protein Alignment CG8888 and Dhrs9

DIOPT Version :9

Sequence 1:NP_610724.1 Gene:CG8888 / 36293 FlyBaseID:FBgn0033679 Length:388 Species:Drosophila melanogaster
Sequence 2:NP_780721.1 Gene:Dhrs9 / 241452 MGIID:2442798 Length:319 Species:Mus musculus


Alignment Length:305 Identity:92/305 - (30%)
Similarity:144/305 - (47%) Gaps:40/305 - (13%)


- Green bases have known domain annotations that are detailed below.


  Fly    96 KGVLITGCEAPLAWYLAKKLDDLGFTVYAGFNTPIEESDEAKILKEVTSGRMKLLHLDVTSEKTI 160
            |.|.||||:.......|:..|..||.|.|...|   ||..| .||..||.|:..:.||||..:.:
Mouse    30 KYVFITGCDTGFGNLAARTFDKKGFRVIAACLT---ESGSA-ALKAKTSERLHTVLLDVTDPENV 90

  Fly   161 LEAARYVSQHLPHGAEGLWSVVHCAHWI-ALGELEWIPFAVLRKSLDLNLLGSARLTQIFLPLVR 224
            .:.|::|..|:  |.:|||.:::.|..: .|...:|:.....|:.:::||.|...:|...||||:
Mouse    91 KKTAQWVKSHV--GEKGLWGLINNAGVLGVLAPTDWLTVDDYREPIEVNLFGLINVTLNMLPLVK 153

  Fly   225 RAHGRVVFLTS--------GLNRVPSPVRGIQCATQAAVDCFAACLRQEMRTRGVDVSVVAAGEF 281
            :|.|||:.::|        |....||         :.||:.|...||::|:..||.||.:..|.|
Mouse   154 KARGRVINVSSIGGRLAFGGGGYTPS---------KYAVEGFNDSLRRDMKAFGVHVSCIEPGLF 209

  Fly   282 APGNGWLNETELRDQAK------QMWNQLSSEQKKTYGEDYYEAAMTSVEKYSRQA-ADIQPTLR 339
                    :|||.|..|      .:|..||.:.|:.|||.|.|.::..::..:... .|:...:.
Mouse   210 --------KTELADPIKTTEKKLAIWKHLSPDIKQQYGEGYIEKSLHRLKSNTSSVNLDLSLVVG 266

  Fly   340 VLIDAVTRTFPMARYTPVTSSERLQIFLAEHLAPSLYESLYGEQK 384
            .:..|:|..||..||.....::...|.|: |:...|.:.|..:||
Mouse   267 CMDHALTSLFPKTRYIAGKDAKTFWIPLS-HMPAVLQDFLLLKQK 310

Known Domains:


Indicated by green bases in alignment.

GeneSequenceDomainRegion External IDIdentity
CG8888NP_610724.1 NADB_Rossmann 96..380 CDD:304358 89/299 (30%)
adh_short 96..293 CDD:278532 65/205 (32%)
Dhrs9NP_780721.1 type2_17beta_HSD-like_SDR_c 30..306 CDD:187665 89/299 (30%)


Information from Original Tools:


Tool Simple Score Weighted Score Original Tool Information
BLAST Result Score Score Type Cluster ID
Compara 00.000 Not matched by this tool.
Domainoid 1 1.000 120 1.000 Domainoid score I5728
eggNOG 1 0.900 - - E1_KOG1610
Hieranoid 1 1.000 - -
Homologene 00.000 Not matched by this tool.
Inparanoid 00.000 Not matched by this tool.
Isobase 00.000 Not matched by this tool.
OMA 1 1.010 - - QHG48608
OrthoDB 00.000 Not matched by this tool.
OrthoFinder 1 1.000 - - FOG0000161
OrthoInspector 1 1.000 - - otm43606
orthoMCL 00.000 Not matched by this tool.
Panther 1 1.100 - - O PTHR43313
Phylome 1 0.910 - -
RoundUp 00.000 Not matched by this tool.
SonicParanoid 1 1.000 - - X110
SwiftOrtho 00.000 Not matched by this tool.
TreeFam 00.000 Not matched by this tool.
98.920

Return to query results.
Submit another query.