DRSC - DRSC Integrative Ortholog Prediction Tool

back to: DIOPT - Ortholog Prediction Tool / DIOPT for Diseases and Traits

Protein Alignment CG8888 and Dhrs9

DIOPT Version :9

Sequence 1:	NP_610724.1	Gene:	CG8888 / 36293	FlyBaseID:	FBgn0033679	Length:	388	Species:	Drosophila melanogaster
Sequence 2:	NP_570832.1	Gene:	Dhrs9 / 170635	RGDID:	620655	Length:	319	Species:	Rattus norvegicus

Alignment Length:	308	Identity:	92/308 - (29%)
Similarity:	148/308 - (48%)	Gaps:	46/308 - (14%)

- Green bases have known domain annotations that are detailed below.

  Fly    96 KGVLITGCEAPLAWYLAKKLDDLGFTVYAGFNTPIEESDEAKILKEVTSGRMKLLHLDVTSEKTI 160
            |.:.||||::......|:..|..||.|.|...|  |...||  ||..||.|:..:.||||:.:.:
  Rat    30 KYIFITGCDSGFGNLAARTFDRKGFRVIAACLT--ESGSEA--LKAKTSERLHTVLLDVTNPENV 90

  Fly   161 LEAARYVSQHLPHGAEGLWSVVHCAHWI-ALGELEWIPFAVLRKSLDLNLLGSARLTQIFLPLVR 224
            .|.|::|..|:  |.:|||.:::.|..: .|...:|:.....|:.:::||.|...:|...||||:
  Rat    91 KETAQWVKSHV--GEKGLWGLINNAGVLGVLAPTDWLTVDDYREPIEVNLFGLINVTLNMLPLVK 153

  Fly   225 RAHGRVVFLTS--------GLNRVPSPVRGIQCATQAAVDCFAACLRQEMRTRGVDVSVVAAGEF 281
            :|.|||:.::|        |....||         :.||:.|...||::|:..||.||.:..|.|
  Rat   154 KARGRVINVSSIGGRLAFGGGGYTPS---------KYAVEGFNDSLRRDMKAFGVHVSCIEPGLF 209

  Fly   282 APGNGWLNETELRDQAK------QMWNQLSSEQKKTYGEDYYEAAMTSVEKYSRQAADIQPTLRV 340
                    :|.|.|..|      .:|..||.:.|:.|||.|.|   .|:.:.....:.:...|.:
  Rat   210 --------KTGLADPIKTTEKKLAIWKHLSPDIKQQYGEGYIE---KSLHRLKSSTSSVNLDLSL 263

  Fly   341 LID----AVTRTFPMARYTPVTSSERLQIFLAEHLAPSLYESLYGEQK 384
            :::    |:|..||..|||....::...|.|: |:..:|.:.|..::|
  Rat   264 VVECMDHALTSLFPKTRYTAGKDAKTFWIPLS-HMPAALQDFLLLKEK 310

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG8888	NP_610724.1	NADB_Rossmann	96..380	CDD:304358	90/302 (30%)
CG8888	NP_610724.1	adh_short	96..293	CDD:278532	65/205 (32%)
Dhrs9	NP_570832.1	type2_17beta_HSD-like_SDR_c	30..306	CDD:187665	90/302 (30%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	1	1.000	120	1.000	Domainoid score	I5601
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	1	1.000	-	-
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	1	1.010	-	-		QHG48608
OrthoDB	1	1.010	-	-		D370032at33208
OrthoFinder	1	1.000	-	-		FOG0000161
OrthoInspector	1	1.000	-	-		otm45679
orthoMCL	0	0.000	Not matched by this tool.
Panther	1	1.100	-	-	O	PTHR43313
Phylome	1	0.910	-	-
SonicParanoid	1	1.000	-	-		X110
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	9	9.030