Protein Alignment CG8888 and SDR9C7

DIOPT Version :10

• Sequence 1: NP_610724.1
• Gene: CG8888 / 36293
• FlyBaseID: FBgn0033679
• Length: 388
• Species: Drosophila melanogaster
• Sequence 2: NP_683695.1
• Gene: SDR9C7 / 121214
• HGNCID: 29958
• Length: 313
• Species: Homo sapiens
• Alignment Length: 285
• Identity: 90/285 - (31%)
• Similarity: 149/285 - (52%)
• Gaps: 17/285 - (5%)

  Fly    94 SGKGVLITGCEAPLAWYLAKKLDDLGFTVYAGFNTPIEESDEAKILKEVTSGRMKLLHLDVTSEK 158
            |.|.|.||||::.....|||:|.|.|..|.|...|  ||..:.  |:..||.|::...||||..:
Human    24 SEKYVFITGCDSGFGNLLAKQLVDRGMQVLAACFT--EEGSQK--LQRDTSYRLQTTLLDVTKSE 84

  Fly   159 TILEAARYVSQHLPHGAEGLWSVVHCAH-WIALGELEWIPFAVLRKSLDLNLLGSARLTQIFLPL 222
            :|..||::|...:  |.:|||::|:.|. .:..|..||:......|.:::||:|...:|...||:
Human    85 SIKAAAQWVRDKV--GEQGLWALVNNAGVGLPSGPNEWLTKDDFVKVINVNLVGLIEVTLHMLPM 147

  Fly   223 VRRAHGRVVFLTSGLNRVPSPVRGIQCATQAAVDCFAACLRQEMRTRGVDVSVVAAGEFAPGNGW 287
            |:||.||||.::|...|| :.:.|..|.::..|:.|:..:|:|:...||.|.::..|.:.  ...
Human   148 VKRARGRVVNMSSSGGRV-AVIGGGYCVSKFGVEAFSDSIRRELYYFGVKVCIIEPGNYR--TAI 209

  Fly   288 LNETELRDQAKQMWNQLSSEQKKTYGEDYYEAAMTSVEKYSRQAADIQPTLRVLID----AVTRT 348
            |.:..|..:.:::|.:|..|.:.:|||||:......::...:.|   :|.:|.:|:    |:...
Human   210 LGKENLESRMRKLWERLPQETRDSYGEDYFRIYTDKLKNIMQVA---EPRVRDVINSMEHAIVSR 271

  Fly   349 FPMARYTPVTSSERLQIFLAEHLAP 373
            .|..||.|...::.|.|.||:...|
Human   272 SPRIRYNPGLDAKLLYIPLAKLPTP 296

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
CG8888	NP_610724.1	Rossmann-fold NAD(P)(+)-binding proteins	96..380	CDD:473865	89/283 (31%)
SDR9C7	NP_683695.1	type2_17beta_HSD-like_SDR_c	26..302	CDD:187665	89/283 (31%)