DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment CG8888 and bdh1b

DIOPT Version :9

Sequence 1:	NP_610724.1	Gene:	CG8888 / 36293	FlyBaseID:	FBgn0033679	Length:	388	Species:	Drosophila melanogaster
Sequence 2:	XP_002937888.2	Gene:	bdh1b / 100497276	XenbaseID:	XB-GENE-22249057	Length:	363	Species:	Xenopus tropicalis

Alignment Length:	319	Identity:	97/319 - (30%)
Similarity:	164/319 - (51%)	Gaps:	18/319 - (5%)

- Green bases have known domain annotations that are detailed below.

  Fly    69 FAVFV-WFALATV--GAVLFYHFVKVSASGKGVLITGCEAPLAWYLAKKLDDLGFTVYAGFNTPI 130
            :.||| |.|:..:  |:        :...||.||||||:....:.|||.|..|||||:||.....
Frog    54 YVVFVLWLAMPAIPRGS--------LPVEGKEVLITGCDTGFGFALAKHLHKLGFTVFAGCLLKD 110

  Fly   131 EESDEAKILKEVTSGRMKLLHLDVTSEKTILEAARYVSQHLPHGAEGLWSVVHCAHWIALGELEW 195
            :..:.|:.|:.:.|.||.:..|:|.:|:.:.:|..:|.||..:..:|||.||:.|.....|::|:
Frog   111 KNGNGAEELQGMQSDRMHVFQLNVCNEEEVAKAVEFVKQHQENPEKGLWGVVNNAGISTFGDVEF 175

  Fly   196 IPFAVLRKSLDLNLLGSARLTQIFLPLVRRAHGRVVFLTSGLNRVPSPVRGIQCATQAAVDCFAA 260
            ......::.:|:||.|:.|:|:.||||:|:|.||||.:.|.|.|:..|.|.....::..|:.|..
Frog   176 TTLDKYKEVMDVNLWGTVRITKAFLPLIRQAKGRVVCVGSTLGRMCKPSRSCYSISKIGVEAFTG 240

  Fly   261 CLRQEMRTRGVDVSVVAAGEFAPGNGWLNETELRDQAKQMWNQLSSEQKKTYGEDYYEAAMTSVE 325
            ||||||...||.|..:.||.|........:..:..:.::||.:.|...:..|.:.:....:|.::
Frog   241 CLRQEMYQWGVKVINIEAGNFIAATELFTKEGVEKRGEEMWEEASDLVRADYRKTHLVHQVTRMK 305

  Fly   326 KY----SRQAADIQPTLRVLIDAVTRTFPMARYTPVTSSERLQIFLAEHLAPSLYESLY 380
            ..    :::..|:   |..:.||:...||..|||...:...::..:..||..::.:.:|
Frog   306 SIVGCGTKETTDV---LNAITDALRSKFPYTRYTLADTYSWIEFQIMSHLPTAIADWIY 361

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG8888	NP_610724.1	NADB_Rossmann	96..380	CDD:304358	89/287 (31%)
CG8888	NP_610724.1	adh_short	96..293	CDD:278532	73/196 (37%)
bdh1b	XP_002937888.2	NADB_Rossmann	76..361	CDD:419666	89/287 (31%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	1	1.000	131	1.000	Domainoid score	I5092
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	1	1.000	-	-		H138151
Inparanoid	1	1.050	159	1.000	Inparanoid score	I4153
OMA	1	1.010	-	-		QHG48608
OrthoDB	1	1.010	-	-		D1390068at2759
OrthoFinder	1	1.000	-	-		FOG0000161
OrthoInspector	1	1.000	-	-		otm48766
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	1	1.030	-	avgDist	Average_Evolutionary_Distance	R1882
SonicParanoid	1	1.000	-	-		X110
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	10	10.010