DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment CG8888 and dhrs7c

DIOPT Version :9

Sequence 1:	NP_610724.1	Gene:	CG8888 / 36293	FlyBaseID:	FBgn0033679	Length:	388	Species:	Drosophila melanogaster
Sequence 2:	XP_012826975.2	Gene:	dhrs7c / 100135266	XenbaseID:	XB-GENE-5956201	Length:	704	Species:	Xenopus tropicalis

Alignment Length:	187	Identity:	44/187 - (23%)
Similarity:	72/187 - (38%)	Gaps:	39/187 - (20%)

- Green bases have known domain annotations that are detailed below.

  Fly   191 GELEWIPFAVLRKSLDLNLLGSARLTQIFLP-LVRRAHGRVVFLTSGLNRVPSPVRGIQCATQAA 254
            |.|:.:...:.:|.:|.|..|...|.:..|| ::.|..|::|.:.:...::..|.|....|::.|
Frog   133 GPLQSVSLELDKKIMDANYFGPITLVKAILPHMISRRTGQIVLVNTIQGKIGVPFRAAYAASKHA 197

  Fly   255 VDCFAACLRQEMRTRGVDVSVVAAG-------EFAPGNGWLNETELRDQAKQMWNQLSSEQKKTY 312
            :..|..|||.|:....|.||.|:..       :..||| |         ...:|..:
Frog   198 IQGFFDCLRAEVEEFDVSVSTVSPTFIRSYHVQPQPGN-W---------EASIWKWI-------- 244

  Fly   313 GEDYYEAAMTS----VEKYSRQAADIQPTLRVLIDAVTRTFPMARYTPVTSSERLQI 365
               :|..||.|    ..:....||...||..|...|      .|.:....:.|||::
Frog   245 ---FYRVAMESPACVASRGQGTAAHGAPTCNVQEKA------NAIWKSCHACERLEV 292

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG8888	NP_610724.1	NADB_Rossmann	96..380	CDD:304358	44/187 (24%)
CG8888	NP_610724.1	adh_short	96..293	CDD:278532	29/109 (27%)
dhrs7c	XP_012826975.2	11beta-HSD1_like_SDR_c	35..257	CDD:187593	34/144 (24%)
dhrs7c	XP_012826975.2	LAP2alpha	425..629	CDD:371604
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	1	0.910