Protein Alignment CG8888 and rdh16

DIOPT Version :10

• Sequence 1: NP_610724.1
• Gene: CG8888 / 36293
• FlyBaseID: FBgn0033679
• Length: 388
• Species: Drosophila melanogaster
• Sequence 2: NP_001107359.1
• Gene: rdh16 / 100135184
• XenbaseID: XB-GENE-1007896
• Length: 317
• Species: Xenopus tropicalis
• Alignment Length: 301
• Identity: 95/301 - (31%)
• Similarity: 154/301 - (51%)
• Gaps: 37/301 - (12%)

  Fly    73 VW-FALATVGAVLFYHF-----VKVSASGKGVLITGCEAPLAWYLAKKLDDLGFTVYAGFNTPIE 131
            :| |.|..:..:|.|.:     :..:.:.|.|.||||::.....|||:||..|..|.|...|
 Frog     1 MWLFLLVLLALILLYRWNIGRKMLPNLTDKYVFITGCDSGFGNLLAKQLDRRGLWVLAACLT--- 62

  Fly   132 ESDEAKILKEVTSGRMKLLHLDVTSEKTILEAARYVSQHLPHGAEGLWSVVHCAHWIA--LGELE 194
             ...|:.||:.||.|:|.:.|:||..::::.|:.:||..:  |.:|||.:|:.| .|:  :...|
 Frog    63 -DKGAEELKKETSSRLKTVILNVTDSQSVISASAWVSDIV--GNKGLWGLVNNA-GISNPIAPNE 123

  Fly   195 WIPFAVLRKSLDLNLLGSARLTQIFLPLVRRAHGRVVFLTSGLNRVPSPVRGIQCATQAAVDCFA 259
            |:......|.|::||||...:|...|||:|:|.||:|.:.|...|| |...|....::..|:.|:
 Frog   124 WLSKEDYLKVLNVNLLGVIDITLKLLPLIRKARGRIVNVASVAGRV-SLCGGGYSISKYGVESFS 187

  Fly   260 ACLRQEMRTRGVDVSVVAAGEFAPGNGWLNETELRD---QAK---QMWNQLSSEQKKTYGEDYYE 318
            ..||:||...|:.||:|..|.|        :|.:.|   |.|   ::|.:|....::|||::|:|
 Frog   188 DSLRREMAQFGIKVSIVEPGYF--------KTPVADANTQKKFLNEIWAKLPQHIRETYGQEYFE 244

  Fly   319 AAMTSVEKYSRQAADIQPTLRVLID----AVTRTFPMARYT 355
            ....:||   |....:...|.::.|    |:|..:|..||:
 Frog   245 KYCNNVE---RNLEKVSSKLHLVTDCMEHALTAVYPRTRYS 282

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
CG8888	NP_610724.1	Rossmann-fold NAD(P)(+)-binding proteins	96..380	CDD:473865	90/272 (33%)
rdh16	NP_001107359.1	type2_17beta_HSD-like_SDR_c	30..306	CDD:187665	90/272 (33%)