Protein Alignment CG8888 and rdh7.2

DIOPT Version :10

• Sequence 1: NP_610724.1
• Gene: CG8888 / 36293
• FlyBaseID: FBgn0033679
• Length: 388
• Species: Drosophila melanogaster
• Sequence 2: NP_001107972.1
• Gene: rdh7.2 / 100135028
• XenbaseID: XB-GENE-1007886
• Length: 317
• Species: Xenopus tropicalis
• Alignment Length: 298
• Identity: 93/298 - (31%)
• Similarity: 148/298 - (49%)
• Gaps: 32/298 - (10%)

  Fly    96 KGVLITGCEAPLAWYLAKKLDDLGFTVYAGFNTPIEESDEAKILKEVTSGRMKLLHLDVTSEKTI 160
            |.||||||::.....||:.||..|..|.|...|    ...|:.||:.||.|::.:.||||...::
 Frog    30 KYVLITGCDSGFGNLLARNLDRRGIRVLAACLT----DRGAEELKKQTSDRLQTVLLDVTDSNSV 90

  Fly   161 LEAARYVSQHLPHGAEGLWSVVH-------CAHWIALGELEWIPFAVLRKSLDLNLLGSARLTQI 218
            ..||.:.||.:  |.:|||.:|:       ||      ..||:......|.:::||||...:|..
 Frog    91 KTAANWASQIV--GDKGLWGLVNNAGISFPCA------PNEWLTKEDFMKVMNVNLLGLIDVTIN 147

  Fly   219 FLPLVRRAHGRVVFLTSGLNRVPSPVRGIQCATQAAVDCFAACLRQEMRTRGVDVSVVAAGEFAP 283
            .|.|:|:|.||||.:.|...|:.....| .|.::..|:.|:..||:|||..||.|.:|..|.|
 Frog   148 MLHLIRKARGRVVNIASVAGRITISGGG-YCMSKYGVESFSDSLRREMRPFGVKVCIVEPGFF-- 209

  Fly   284 GNGWLNETELRDQA-KQMWNQLSSEQKKTYGEDYYE----AAMTSVEKYSRQAADIQPTLRVLID 343
             ...:..|:|..|: ::.||..:.|.:::||::|::    |:.|.|....   |::......|..
 Frog   210 -KTQITNTDLVKQSLERAWNSTTEEIRQSYGQEYFKKSCNASQTIVPLCK---ANLSLVTDCLEH 270

  Fly   344 AVTRTFPMARYTPVTSSERLQIFLAEHLAPSLYESLYG 381
            |:|...|..||:....::.|.:.|: :...|:.:.|.|
 Frog   271 ALTAAHPRTRYSAGWDAKLLFLPLS-YFPTSVVDFLLG 307

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
CG8888	NP_610724.1	Rossmann-fold NAD(P)(+)-binding proteins	96..380	CDD:473865	91/295 (31%)
rdh7.2	NP_001107972.1	type2_17beta_HSD-like_SDR_c	30..306	CDD:187665	91/295 (31%)