DRSC - DRSC Integrative Ortholog Prediction Tool

back to: DIOPT - Ortholog Prediction Tool / DIOPT for Diseases and Traits

Protein Alignment Drep3 and Dffa

DIOPT Version :9

Sequence 1:	NP_610722.2	Gene:	Drep3 / 36292	FlyBaseID:	FBgn0028407	Length:	266	Species:	Drosophila melanogaster
Sequence 2:	NP_001020467.1	Gene:	Dffa / 13347	MGIID:	1196227	Length:	331	Species:	Mus musculus

Alignment Length:	192	Identity:	54/192 - (28%)
Similarity:	79/192 - (41%)	Gaps:	43/192 - (22%)

- Green bases have known domain annotations that are detailed below.

  Fly    91 LALSPHSSATPTPSPTTADEDFAQLDNSKPFKIKDITRNIRK---AVVATTLSELRTKVS--LKF 150
            :.||..:||   |.|          |:.:|.|...:.||..:   .|.|::|.|||:|..  |..
Mouse     1 MELSRGASA---PDP----------DDVRPLKPCLLRRNHSRDQHGVAASSLEELRSKACELLAI 52

  Fly   151 ERAQPAIHLDC--DGTEVDDEEYFSTLEPNAELIAVFPGEQW--RDPSDYNANLRRTSLDAQRLR 211
            :::...|.|..  |||.|||::||..|..|.:.:|:...|:|  .|.....|.:.:.|.:|....
Mouse    53 DKSLTPITLVLAEDGTIVDDDDYFLCLPSNTKFVALACNEKWIYNDSDGGTAWVSQESFEADEPD 117

  Fly   212 SLVSKLQPNYMND--DDLDK---LSNMDPNSLVDITGREPKDNEYSARSDAARLSTEL--SC 266
            |.......|....  :||..   ||..|..:|:||              ..|.|:.||  ||
Mouse   118 SRAGVKWKNVARQLKEDLSSIILLSEEDLQALIDI--------------PCAELAQELCQSC 165

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
Drep3	NP_610722.2	CIDE_N	119..192	CDD:119367	27/81 (33%)
Dffa	NP_001020467.1	CIDE_N_ICAD	17..96	CDD:119369	27/78 (35%)
		DFF-C	100..263	CDD:286165	19/80 (24%)
		Disordered. /evidence=ECO:0000256\|SAM:MobiDB-lite	306..331
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C167849544
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	2	1.840