DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment Drep1 and cideb

DIOPT Version :9

Sequence 1:	NP_001260909.1	Gene:	Drep1 / 36290	FlyBaseID:	FBgn0024732	Length:	306	Species:	Drosophila melanogaster
Sequence 2:	NP_001243186.1	Gene:	cideb / 553467	ZFINID:	ZDB-GENE-080514-2	Length:	208	Species:	Danio rerio

Alignment Length:	245	Identity:	54/245 - (22%)
Similarity:	96/245 - (39%)	Gaps:	64/245 - (26%)

- Green bases have known domain annotations that are detailed below.

  Fly     1 METAANSGDS---------KKPFKVKDVTRNIKKAVCASSLEEIRSKVAEKFEKCDHLPTIHLDS 56
            |||.::...|         ::||:|....|.:||.:.|.:|||::.:..:.. ....:.|:..:.
Zfish     1 METTSSLFKSVSRRVWSPPQRPFRVCSWNREVKKGITAGTLEELKERAGQAL-LISKMLTLVCEE 64

  Fly    57 DGTEIDDEEYFRTLDENTELVAVFPGEHWIDPTHYVTITTPHGNEAGTGNGELNGGGEGDTTDAN 121
            ||||:|.:|:...|.:||..:.:.|.|.|          .||......||      ..||:....
Zfish    65 DGTEVDSDEFLIALPDNTVFMCLQPEEIW----------KPHPLHQRGGN------KPGDSKPRT 113

  Fly   122 NSESARI---------RQLVGQLQ-----NNLCNVSVMNDADLDSLSNMDPNSLVDITGKEFMEQ 172
            ..:.|:|         :.:.|.|.     ..|.:||    ||...|.           .|:|
Zfish   114 GKDIAQITFDLYRTHPKDVFGSLNVKATYQGLYSVS----ADFQCLG-----------PKKF--- 160

  Fly   173 LKDAGRPLCAKRNAEDRLNLLKLLKAGAIFCSERYPEDAEAIDREIGRQL 222
            |::|.:.:....:|...|    |:.:.|:.  .|..:.|:.:..:..:|:
Zfish   161 LREALKMMSTLLHAAGHL----LISSAAVI--RRIIQGADMLQAQNNKQI 204

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
Drep1	NP_001260909.1	CAD	12..85	CDD:128562	22/72 (31%)
cideb	NP_001243186.1	CIDE-N	20..93	CDD:280235	22/73 (30%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	1	1.000	-	-		FOG0001779
OrthoInspector	1	1.000	-	-		mtm6534
orthoMCL	0	0.000	Not matched by this tool.
Panther	1	1.100	-	-	O	PTHR12306
Phylome	1	0.910	-	-
RoundUp	1	1.030	-	avgDist	Average_Evolutionary_Distance	R4920
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
ZFIN	0	0.000	Not matched by this tool.
	5	5.040