DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment Drep1 and dffa

DIOPT Version :9

Sequence 1:	NP_001260909.1	Gene:	Drep1 / 36290	FlyBaseID:	FBgn0024732	Length:	306	Species:	Drosophila melanogaster
Sequence 2:	XP_002939454.3	Gene:	dffa / 548407	XenbaseID:	XB-GENE-946586	Length:	300	Species:	Xenopus tropicalis

Alignment Length:	242	Identity:	58/242 - (23%)
Similarity:	106/242 - (43%)	Gaps:	47/242 - (19%)

- Green bases have known domain annotations that are detailed below.

  Fly    24 KKAVCASSLEEIRSKVAEKFEKCDHLP--TIHLDSDGTEIDDEEYFRTLDENTELVAVFPGEHWI 86
            :..|.|:||||:..|..:||.....:.  |:.|..|||.::||:||..|..||:.|.:...:.|.
Frog    18 RHGVAAASLEELLEKACKKFSLDSSVEPITLVLAEDGTIVEDEDYFLCLPPNTKFVILTGNKKWA 82

  Fly    87 DPTHYVTITTPHGNEAGTGNGELNGGGEGDTTDANNSESA---RIRQLVGQLQNNLCNVSVMNDA 148
            .       ||..|..|......:      :..|.|..:.|   |.:.|..||:.:|.|:.:|:::
Frog    83 P-------TTLDGGTAWLARDSM------EVEDENMVDGADLTRWKNLALQLKEDLSNIILMSES 134

  Fly   149 DLDSLSNMDPNSLVDITGK--EFMEQLKDAGRPLCAKRNAE-DRLNLLKLLKAGAIFCSERYPED 210
            :|..|:.:..:.|..:.|.  |.::.|::..:.:..:|..| ....||:|.
Frog   135 ELQILTEVSVDELAGVVGVSCEKVQSLQNIIQRVMDRREEERQSKQLLELY-------------- 185

  Fly   211 AEAIDRE-------IGRQLNEAESG-----QMSTTTTSNTRTIEVVQ 245
            .||:.:|       |....:|.:||     |:|..:..::..:|:::
Frog   186 LEAVKKEKTSEPDSIYFAEDEVDSGGNTQTQLSCKSLVSSHIMEILK 232

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
Drep1	NP_001260909.1	CAD	12..85	CDD:128562	22/62 (35%)
dffa	XP_002939454.3	CIDE_N_ICAD	4..83	CDD:119369	23/64 (36%)
dffa	XP_002939454.3	DFF-C	87..250	CDD:401104	33/166 (20%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	1	1.010	-	-		D1564672at2759
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
Panther	1	1.100	-	-	O	PTHR12306
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	3	3.020