Protein Alignment Drep1 and DFFA

DIOPT Version :10

• Sequence 1: NP_001260909.1
• Gene: Drep1 / 36290
• FlyBaseID: FBgn0024732
• Length: 306
• Species: Drosophila melanogaster
• Sequence 2: NP_004392.1
• Gene: DFFA / 1676
• HGNCID: 2772
• Length: 331
• Species: Homo sapiens
• Alignment Length: 326
• Identity: 71/326 - (21%)
• Similarity: 128/326 - (39%)
• Gaps: 104/326 - (31%)

  Fly     1 METAANSG-------DSKKPFKVKDVTRNIKK---AVCASSLEEIRSKVAEKFEKCDHLP----- 50
            ||...::|       .:.||..::   ||..:   .|.||.||::|||.      ||.|.
Human     1 MEVTGDAGVPESGEIRTLKPCLLR---RNYSREQHGVAASCLEDLRSKA------CDILAIDKSL 56

  Fly    51 ---TIHLDSDGTEIDDEEYFRTLDENTELVAVFPGEHWIDPTHYVTITTPHGNEAGTG--NGELN 110
               |:.|..|||.:||::||..|..||:.||:...|.|          ..:.::.||.  :.|
Human    57 TPVTLVLAEDGTIVDDDDYFLCLPSNTKFVALASNEKW----------AYNNSDGGTAWISQE-- 109

  Fly   111 GGGEGDTTDANNSESARIRQLVGQLQNNLCNVSVMNDADLDSLSNMDPNSLVDITGKEFMEQLKD 175
               ..|..:.::....:.:.:..||:.:|.::.::::.||        ..|||....:..::|:.
Human   110 ---SFDVDETDSGAGLKWKNVARQLKEDLSSIILLSEEDL--------QMLVDAPCSDLAQELRQ 163

  Fly   176 AGRPLCAK------------------RNAED--RLNLLKLLKAGAIFCSER-----YPEDAEAID 215
            :    ||.                  |.::.  :|.|..|.|.|::...:.     :.|:.:|:|
Human   164 S----CATVQRLQHTLQQVLDQREEVRQSKQLLQLYLQALEKEGSLLSKQEESKAAFGEEVDAVD 224

  Fly   216 REIGRQ--------------LNEAESGQMSTT-------TTSNTRTIEVVQCDNQNTTITITVGE 259
            ..|.|:              |.|.::.::|.:       |..:.:.:.|..  |.:...|.||.|
Human   225 TGISRETSSDVALASHILTALREKQAPELSLSSQDLELVTKEDPKALAVAL--NWDIKKTETVQE 287

  Fly   260 A 260
            |
Human   288 A 288

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Drep1	NP_001260909.1	CAD	12..85	CDD:128562	30/83 (36%)
DFFA	NP_004392.1	CIDE_N	18..96	CDD:470607	31/96 (32%)
		DFF-C	100..264	CDD:462661	29/180 (16%)
		Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite	305..331